Evidence map›Paper›PMID 35665983›Full record

ArticleHuman brain mapping2022

Causal effects of cingulate morphology on executive functions in healthy young adults.

Fuleah A Razzaq, Maria L Bringas Vega, Marlis Ontiveiro-Ortega, Usama Riaz, Pedro A Valdes-Sosa

Abstract read
In one paragraph

Article in Human brain mapping, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fuleah A RazzaqThe Clinical Hospital of Chengdu Brain Sciences, University of Electronic Science and Technology of China, Chengdu, China.ORCID 0000-0002-4334-8029
Maria L Bringas VegaThe Clinical Hospital of Chengdu Brain Sciences, University of Electronic Science and Technology of China, Chengdu, China.
Marlis Ontiveiro-OrtegaCuban Neuroscience Center, Havana, Cuba.
Usama RiazThe Clinical Hospital of Chengdu Brain Sciences, University of Electronic Science and Technology of China, Chengdu, China.
Pedro A Valdes-SosaThe Clinical Hospital of Chengdu Brain Sciences, University of Electronic Science and Technology of China, Chengdu, China.ORCID 0000-0001-5485-2661

Funding

Mapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7M
NIMH NIH HHS U54 MH091657
6 · The paper itself

Abstract

In this study, we want to explore evidence for the causal relationship between the anatomical descriptors of the cingulate cortex (surface area, mean curvature-corrected thickness, and volume) and the performance of cognitive tasks such as Card Sort, Flanker, List Sort used as instruments to measure the executive functions of flexibility, inhibitory control, and working memory. We have performed this analysis in a cross-sectional sample of 899 healthy young subjects of the Human Connectome Project. To the best of our knowledge, this is the first study using causal inference to explain the relationship between cingulate morphology and the performance of executive tasks in healthy subjects. We have tested the causal model under a counterfactual framework using stabilized inverse probability of treatment weighting and marginal structural models. The results showed that the posterior cingulate surface area has a positive causal effect on inhibition (Flanker task) and cognitive flexibility (Card Sort). A unit increase (+1 mm

Indexed as

ConnectomeExecutive FunctionCerebral CortexCross-Sectional StudiesHumansMemory, Short-TermYoung Adultbrain executive functionscausal inferencecingulate cortexcounterfactual frameworkinverse probability of treatment weightingmarginal structural models

Identifiers

PMID35665983
PMCPMC9435009

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.