Evidence map›Paper›PMID 35665919›Full record

ArticleAustralian veterinary journal2022

Seropositivity to Campylobacter and association with abortion and lamb mortality in maiden ewes from Western Australia, South Australia and Victoria.

T Clune, M Bruce, E Glanville, Ajd Campbell, A Lockwood, S Hancock, A N Thompson, S Beetson, D Brookes, C Trengove and 2 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Australian veterinary journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

T CluneCentre for Animal Production and Health, Food Futures Institute, Murdoch University, South Street, Murdoch, Western Australia, 6150, Australia.
M BruceCentre for Biosecurity and One Health, Harry Butler Institute, Murdoch University, South Street, Murdoch, Western Australia, 6150, Australia.
E GlanvilleMackinnon Project, Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Werribee, Victoria, 3030, Australia.
Ajd CampbellNossal Institute for Global Health, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, 3010, Australia.
A LockwoodCentre for Animal Production and Health, Food Futures Institute, Murdoch University, South Street, Murdoch, Western Australia, 6150, Australia.
S HancockCentre for Animal Production and Health, Food Futures Institute, Murdoch University, South Street, Murdoch, Western Australia, 6150, Australia.
A N ThompsonCentre for Animal Production and Health, Food Futures Institute, Murdoch University, South Street, Murdoch, Western Australia, 6150, Australia.
S BeetsonCentre for Animal Production and Health, Food Futures Institute, Murdoch University, South Street, Murdoch, Western Australia, 6150, Australia.
D BrookesMackinnon Project, Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Werribee, Victoria, 3030, Australia.
C TrengoveSchool of Animal and Veterinary Sciences, University of Adelaide, Roseworthy, South Australia, 5371, Australia.
R O'HandleySchool of Animal and Veterinary Sciences, University of Adelaide, Roseworthy, South Australia, 5371, Australia.
C JacobsonCentre for Animal Production and Health, Food Futures Institute, Murdoch University, South Street, Murdoch, Western Australia, 6150, Australia.ORCID https://orcid.org/0000-0001-9427-1941
Murdoch University · AUThe University of Melbourne · AUThe University of Adelaide · AU

Funding

Meat and Livestock Australia B.AHE.0318Murdoch University Veterinary TrustSheep Industry Business Innovation (Department of Primary Industries and Regional Development, Western Australia)
6 · The paper itself

Abstract

This case-control study investigated associations between Campylobacter fetus or Campylobacter jejuni titre and reproductive outcomes in 22 flocks of Merino and non-Merino maiden ewes aged 1-2 years old. Campylobacter titres were also determined for multiparous ewes aged 3 years or older on the same farms. C. fetus 'positivity' (titre ≥1:80) was detected for 12% (57/462; 95% confidence interval [95% CI] 9.6 to 15.6) of maiden ewes and 31% (65/210; 95% CI 25.0 to 37.4) of mature ewes. The odds for failing to rear a lamb in C. fetus-'exposed' maiden ewes (titre ≥1:10) was 2.01 times that of seronegative ewes (95% CI 1.09 to 3.77; P = 0.027), but there was no association between C. fetus-'positivity' (titre ≥1:80) and failure to rise (OR 1.69; 95% CI 0.77 to 3.76; P = 0.191). C. fetus abortions were confirmed with microbial culture in one maiden ewe flock. In this flock, C. fetus titres fluctuated and often waned by lamb marking, highlighting the value of necropsies during abortion investigations. C. jejuni-'positivity' (titre ≥1:80) was detected for 44% (204/462; 95% CI 39.7 to 48.7) maiden ewes, but odds of failing to rear were decreased for C. jejuni-'positive' ewes (OR 0.52; 95% CI 0.32 to 0.83; P = 0.007). The association between Campylobacter serology and the reproductive outcome was inconsistent in these flocks. Serology should be considered in the context of other risk factors and used in conjunction with other strategies to investigate the impact of Campylobacter exposure on ewe reproductive performance such as monitoring for abortions and lamb necropsies to determine aetiological diagnosis, and vaccination trials.

Indexed as

CampylobacterSheep DiseasesAnimalsCase-Control StudiesFemalePregnancySheepSouth AustraliaVictoriaWestern Australiaabortionlamb survivalmortalityovine campylobacteriosisprimiparous ewesheep

Identifiers

PMID35665919
PMCPMC9544749
OpenAlexW4281771368

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.