Evidence map›Paper›PMID 35665917›Full record

ArticlePhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology2022

Ibuprofen molecular aggregation by direct back-face transmission steady-state fluorescence.

Paula Y Steinberg, Nicolás I Krimer, Gabriela P Sarmiento, Darío Rodrigues, Cristián Huck-Iriart, Daniel Clemens, Andrés Zelcer, Martín Mirenda

Abstract read
In one paragraph

Article in Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Paula Y SteinbergGerencia Química, Centro Atómico Constituyentes, Comisión Nacional de Energía Atómica (CNEA-CONICET), Av. Gral. Paz 1499, San Martín, B1650KNA, Buenos Aires, Argentina.ORCID http://orcid.org/0000-0001-5857-7046
Nicolás I KrimerGerencia Química, Centro Atómico Constituyentes, Comisión Nacional de Energía Atómica (CNEA-CONICET), Av. Gral. Paz 1499, San Martín, B1650KNA, Buenos Aires, Argentina.ORCID http://orcid.org/0000-0003-0261-827X
Gabriela P SarmientoGerencia Química, Centro Atómico Constituyentes, Comisión Nacional de Energía Atómica (CNEA-CONICET), Av. Gral. Paz 1499, San Martín, B1650KNA, Buenos Aires, Argentina.ORCID http://orcid.org/0000-0001-5945-9359
Darío RodriguesGerencia Química, Centro Atómico Constituyentes, Comisión Nacional de Energía Atómica (CNEA-CONICET), Av. Gral. Paz 1499, San Martín, B1650KNA, Buenos Aires, Argentina.ORCID http://orcid.org/0000-0002-7952-7168
Cristián Huck-IriartInstituto de Tecnologías Emergentes y Ciencias Aplicadas (ITECA), UNSAM-CONICET, Escuela de Ciencia y Tecnología, Laboratorio de Cristalografía Aplicada, Campus Miguelete, 25 de Mayo y Francia, 1650 San Martín, Buenos Aires, Argentina.ORCID http://orcid.org/0000-0001-5734-2499
Daniel ClemensHelmholtz-Zentrum Berlin, Hahn-Meitner-Platz 1, 14109, Berlin, Germany.
Andrés ZelcerCIBION, CONICET, Godoy Cruz 2390, C1425FQD, Buenos Aires, Argentina.ORCID http://orcid.org/0000-0002-0101-3239
Martín MirendaGerencia Química, Centro Atómico Constituyentes, Comisión Nacional de Energía Atómica (CNEA-CONICET), Av. Gral. Paz 1499, San Martín, B1650KNA, Buenos Aires, Argentina. mirenda@cnea.gov.ar.ORCID http://orcid.org/0000-0003-0478-5178

Funding

Fondo para la Investigación Científica y Tecnológica PICT2018-02153Fondo para la Investigación Científica y Tecnológica PICT2019-01615Fondo para la Investigación Científica y Tecnológica PICT2019-02034International Atomic Energy Agency EVT1901584-0001-ARG
6 · The paper itself

Abstract

Direct back-face transmission steady-state fluorescence was successfully applied to the study of aggregation of ibuprofen and ibuprofenate anion in solution taking advantage of its own fluorescence. The analysis of the experimental data involves the use of the differential reabsorption model to account for re-absorption phenomenon and the closed association model to describe aggregation. The fluorescence quantum yield of ibuprofenate increases when it aggregates in the presence of sodium, but it markedly decreases when 1-butyl-3-methylimidazolium is used as counterion. The proposed methodology allows the accurate determination of the critical aggregation concentrations and the mean aggregation numbers. Results were supported by complementary techniques such as time-resolved fluorescence,

Indexed as

IbuprofenSurface-Active AgentsAnionsMagnetic Resonance SpectroscopyAnionsIbuprofenSurface-Active AgentsAggregationAmphipathic moleculesFluorescence quantum yieldIbuprofen

Identifiers

PMID35665917
PMCPMC9166242

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.