Evidence map›Paper›PMID 35665899›Full record

ArticleBiomolecular NMR assignments2022

Jessica L Davis, Andrea M Hounslow, Nicola J Baxter, Stéphane Mesnage, Mike P Williamson

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecular NMR assignments, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 0 citations in OpenAlex.

  1. mBio · 2026
    Article
  2. bioRxiv : the preprint server for biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jessica L DavisSchool of Biosciences, University of Sheffield, Firth Court, Western Bank, S10 2TN, Sheffield, UK.ORCID 0000-0002-3179-0098
Andrea M HounslowSchool of Biosciences, University of Sheffield, Firth Court, Western Bank, S10 2TN, Sheffield, UK.
Nicola J BaxterSchool of Biosciences, University of Sheffield, Firth Court, Western Bank, S10 2TN, Sheffield, UK.
Stéphane MesnageSchool of Biosciences, University of Sheffield, Firth Court, Western Bank, S10 2TN, Sheffield, UK.ORCID 0000-0001-5572-1903
Mike P WilliamsonSchool of Biosciences, University of Sheffield, Firth Court, Western Bank, S10 2TN, Sheffield, UK. m.williamson@sheffield.ac.uk.ORCID 0000-0003-1648-4890
University of Sheffield · GB

Funding

Biotechnology and Biological Sciences Research Council BB/M011151/1
6 · The paper itself

Abstract

Enterococcus faecalis is a major causative agent of hospital acquired infections. The ability of E. faecalis to evade the host immune system is essential during pathogenesis, which has been shown to be dependent on the complete separation of daughter cells by peptidoglycan hydrolases. AtlE is a peptidoglycan hydrolase which is predicted to bind to the cell wall of E. faecalis, via six C-terminal repeat sequences. Here, we report the near complete assignment of one of these six repeats, as well as the predicted backbone structure and dynamics. This data will provide a platform for future NMR studies to explore the ligand recognition motif of AtlE and help to uncover its potential role in E. faecalis virulence.

Indexed as

Enterococcus faecalisN-Acetylmuramoyl-L-alanine AmidaseBacterial ProteinsCell WallLigandsNuclear Magnetic Resonance, BiomolecularPeptidoglycanBacterial ProteinsLigandsN-Acetylmuramoyl-L-alanine AmidasePeptidoglycanAtlEE. faecalisHydrolasePeptidoglycanR6

Identifiers

PMID35665899
PMCPMC9510096
OpenAlexW4281681052

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.