ArticleEpidemics2022
Modeling waning and boosting of COVID-19 in Canada with vaccination.
Article in Epidemics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Predictive models for health outcomes due to SARS-CoV-2, including the effect of vaccination: a systematic review.Systematic reviews · 2024Pooled it
- Assessing the Impact of COVID-19 Vaccination Programs on the Reduction of COVID-19 Cases: A Systematic Literature Review.Annals of global health · 2024Pooled it
- Epidemiological impacts of nonpharmaceutical interventions are modulated by immunity exposure trade offs.Communications medicine · 2026Article
- The tale of two assumptions: incorporating healthcare-seeking behaviour in epidemic forecasting.BMC infectious diseases · 2025Article
- Evaluating COVID-19 vaccination policy in Québec (Canada) using a data-driven dynamic transmission model.PLoS computational biology · 2025Article
- Learning from the COVID-19 pandemic: A systematic review of mathematical vaccine prioritization models.Infectious Disease Modelling · 2024Review
- Learning from the COVID-19 pandemic: a systematic review of mathematical vaccine prioritization models.medRxiv : the preprint server for health sciences · 2024Article
- Differentiating behavioral impact with or without vaccination certification under mass vaccination and non-pharmaceutical interventions on mitigating COVID-19.Scientific reports · 2024Article
- Impact of recruitment strategies on individual participation practices in the Canadian National Vaccine Safety Network: prospective cohort study.Frontiers in public health · 2024Article
- Canadian Covid-19 pandemic public health mitigation measures at the province level.Scientific data · 2023Article
- Pharmaceutical and non-pharmaceutical interventions for controlling the COVID-19 pandemic.Royal Society open science · 2023Article
- Effects of boosting and waning in highly exposed populations on dengue epidemic dynamics.Science translational medicine · 2023Article
- Multiple cohort study of hospitalized SARS-CoV-2 in-host infection dynamics: Parameter estimates, identifiability, sensitivity and the eclipse phase profile.Journal of theoretical biology · 2023Article
- COVID-19 Vaccination and Healthcare Demand.Bulletin of mathematical biology · 2023Article
- COVID-19 endgame: From pandemic to endemic? Vaccination, reopening and evolution in low- and high-vaccinated populations.Journal of theoretical biology · 2023Article
- Long-term durability of immune responses to the BNT162b2 and mRNA-1273 vaccines based on dosage, age and sex.Scientific reports · 2022Article
- Measuring the impact of COVID-19 vaccination and immunity waning: A modelling study for Portugal.Vaccine · 2022Article
- The resurgence risk of COVID-19 in China in the presence of immunity waning and ADE: A mathematical modelling study.Vaccine · 2022Article
- SARS-CoV-2 transmission and impacts of unvaccinated-only screening in populations of mixed vaccination status.Nature communications · 2022Article
- SARS-CoV-2 Transmission and Impacts of Unvaccinated-Only Screening in Populations of Mixed Vaccination Status.medRxiv : the preprint server for health sciences · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
SARS-CoV-2, the causative agent of COVID-19, has caused devastating health and economic impacts around the globe since its appearance in late 2019. The advent of effective vaccines leads to open questions on how best to vaccinate the population. To address such questions, we developed a model of COVID-19 infection by age that includes the waning and boosting of immunity against SARS-CoV-2 in the context of infection and vaccination. The model also accounts for changes to infectivity of the virus, such as public health mitigation protocols over time, increases in the transmissibility of variants of concern, changes in compliance to mask wearing and social distancing, and changes in testing rates. The model is employed to study public health mitigation and vaccination of the COVID-19 epidemic in Canada, including different vaccination programs (rollout by age), and delays between doses in a two-dose vaccine. We find that the decision to delay the second dose of vaccine is appropriate in the Canadian context. We also find that the benefits of a COVID-19 vaccination program in terms of reductions in infections is increased if vaccination of 15-19 year olds are included in the vaccine rollout.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.