Evidence map›Paper›PMID 35665566›Full record

SynthesisNeurogastroenterology and motility2022

Normative values for esophageal functional lumen imaging probe measurements: A meta-analysis.

Albert J Bredenoord, Francesca Rancati, Haiying Lin, Naama Schwartz, Mirit Argov

Abstract readMeta-AnalysisReview
In one paragraph

Synthesis in Neurogastroenterology and motility, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  14. Physiology of lower gastrointestinal tract.Alimentary pharmacology & therapeutics · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Albert J BredenoordDepartment of Gastroenterology and Hepatology, Amsterdam UMC, Amsterdam, The Netherlands.
Francesca RancatiMedtronic, Minneapolis, Minnesota, USA.
Haiying LinMedtronic, Minneapolis, Minnesota, USA.
Naama SchwartzMedtronic, Minneapolis, Minnesota, USA.
Mirit ArgovMedtronic, Minneapolis, Minnesota, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe functional lumen imaging probe (Endoflip™) is increasingly used for evaluation of patients with esophageal symptoms. To improve the interpretation of Endoflip™ in clinical practice, normative values with appropriate cut-off values are required.

methodsOriginal clinical studies describing Endoflip™ use for measurements of esophageal motility in healthy adults were considered. Meta-analysis was performed based on published values.

resultsA total of 17 articles were included in the systematic review, 15 of which were included in the meta-analysis, representing 154 unique subjects. At 40 ml distention, the 5th-95th and 10th-90th percentiles for esophagogastric junction distensibility index (EGJ-DI) were 1.96-10.95 mm

conclusionsGiven these observations, we recommend using a cut-off of 2 mm

Indexed as

Esophageal AchalasiaAdultDiagnostic ImagingEsophagogastric JunctionHealthy VolunteersHumansManometryachalasiacatheterdysphagiaesophagusmanometryreflux disease

Identifiers

PMID35665566
PMCPMC9786273

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.