Evidence map›Paper›PMID 35665513›Full record

ArticleThe Veterinary record2022

UK veterinary professionals' perceptions and experiences of adverse drug reaction reporting.

Heather Davies, Gina Pinchbeck, Peter-John M Noble, Gillian Diesel, Munir Pirmohamed, Nadine Anderson, David R Killick

Open access · hybridAbstract read
In one paragraph

Article in The Veterinary record, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Heather DaviesInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Neston, UK.ORCID 0000-0001-6905-4718
Gina PinchbeckInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Neston, UK.
Peter-John M NobleInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Neston, UK.
Gillian DieselPharmacovigilance Unit, Veterinary Medicines Directorate, Addlestone, UK.
Munir PirmohamedWolfson Centre for Personalised Medicine, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.
Nadine AndersonPharmacovigilance Unit, Veterinary Medicines Directorate, Addlestone, UK.
David R KillickInstitute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Neston, UK.
University of Liverpool · GBVeterinary Medicines Directorate · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

backgroundSpontaneous reporting of suspected adverse drug reactions (ADRs) is the cornerstone of pharmacovigilance. Despite this, it is believed that there is significant under-reporting in the veterinary setting. Low reporting rates delay marketing authorisation holders (MAHs) and regulators taking mitigating action in the case of safety concerns.

methodWe designed a survey to explore the perceptions, attitudes and experiences of UK veterinary professionals towards ADR reporting. The survey was advertised widely through conventional and social media and at several conferences.

resultsIn total, 260 respondents completed the survey, including 210 veterinary surgeons, 49 veterinary nurses and one suitably qualified person. Respondents generally understood the need to report ADRs. The main barrier to reporting was the suspected ADR being well known, and the most popular potential facilitator identified was the ability to report via the practice management system. Facilitation via education in the form of a pharmacovigilance themed continuing professional development event was particularly popular among veterinary nurses, who reported time as being less of a barrier to reporting than their veterinary surgeon counterparts.

conclusionsOur findings suggest that technological interventions to facilitate reporting and empowerment of veterinary nurses to report through a tailored training event should be explored further.

Indexed as

Drug-Related Side Effects and Adverse ReactionsVeterinariansAdverse Drug Reaction Reporting SystemsAnimalsHealth Knowledge, Attitudes, PracticeHumansPharmacovigilanceUnited Kingdom

Identifiers

PMID35665513
PMCPMC9795988
OpenAlexW4281755043

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.