ArticleBrain imaging and behavior2022
The distinct disrupted plasticity in structural and functional network in mild stroke with basal ganglia region infarcts.
Article in Brain imaging and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Resting-state functional connectivity alterations in post-stroke cognitive impairment: a systematic review.Brain imaging and behavior · 2025Pooled it
- Enhanced hippocampal-cortical functional connectivity following post-stroke cognitive impairment: a resting-state functional magnetic resonance imaging study.Quantitative imaging in medicine and surgery · 2026Article
- The Cerebellar Connectome Disruptions in Ischemic Stroke.CNS neuroscience & therapeutics · 2026Article
- Disrupted intrinsic functional brain topology in patients with basal ganglia ischemic stroke.Quantitative imaging in medicine and surgery · 2025Article
- Repetitive Transcranial Magnetic Stimulation Improves Cognitive Impairment via the Regulation of White Matter Injury in Rats With Ischemic Stroke.Brain and behavior · 2025Article
- Unravelling the nexus of stroke and dementia: Deciphering the role of secondary neurodegeneration in orchestrating cognitive decline.Neuroprotection (Chichester, England) · 2025Review
- Left Basal Ganglia Stroke-induced more Alterations of Functional Connectivity: Evidence from an fMRI StudyCurrent medical imaging · 2025Article
- Cognitive impairment after intravenous thrombolysis in mild stroke: assessment of cerebral blood flow covariance network.Frontiers in neurology · 2025Article
- Structural network disruption of corticothalamic pathways in cerebral small vessel disease.Brain imaging and behavior · 2024Article
- Exploring the Relationship between Abnormal Communication Efficiency of Cerebral Cortex and Multiple Cognitive Functions in Mild Subcortical Stroke: A Resting-State fMRI Study.Brain sciences · 2024Article
- Association Analysis of Gut Microbiota and Prognosis of Patients with Acute Ischemic Stroke in Basal Ganglia Region.Microorganisms · 2023Article
- Brain disconnections refine the relationship between brain structure and function.Brain structure & function · 2022Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 2 countries.
Funding
Abstract
Stroke induced by basal ganglia infarction often impair cognitive function. The exploration of topological patterns in structural and functional networks associated cognitive impairment after stroke may contribute to understand the pathological mechanism of cognitive impairment caused by stroke. In this paper, graph theory analysis was applied to diffusion-weighted imaging (DWI) data and resting-state functional MRI (fMRI) data from 23 post-stroke patients with cognitive impairment (PSCI), 17 post-stroke patients without cognitive impairment (NPSCI), and 29 healthy controls (HC). Structural and functional connectivity between 90 cortical and subcortical brain regions was estimated and set threshold to construct a set of undirected graphs. Network-based statistics (NBS) was used to characterize altered connectivity patterns among the three groups. Compared to HC, the PSCI group demonstrated substantial reductions in all three types of connections-rich club, feeder, and local-in structural and functional networks. Specifically, in structural network analysis, reduced connections were observed within basal ganglia and basal ganglia-frontal networks, whereas in the functional network analysis, reduced connections were observed in fronto-parietal network (FPN) and cingulo-opercular networks (CON). Meanwhile, compared to HC, the NPSCI group demonstrated reductions in both feeder and local connections only within occipital area and occipital-temporal structural networks. The findings of reduced structural connectivity in regions stemming from a basal ganglia core and reduced functional connectivity in FPN and CON may indicate a bottom-up cognitive impairment induced by stroke. Graph analysis and connectomics may aid clinical diagnosis and serve as potential imaging biomarkers for post-stroke patients with cognitive impairment.
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Registered trials
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