Evidence map›Paper›PMID 35665348›Full record

ArticleFrontiers in medicine2022

Increased Cardiovascular Risk in Psoriatic Arthritis: Results From a Case-Control Monocentric Study.

Yannick Degboé, Richard Koch, Laurent Zabraniecki, Bénédicte Jamard, Guillaume Couture, Jean Bernard Ruidavets, Jean Ferrieres, Adeline Ruyssen-Witrand, Arnaud Constantin

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yannick DegboéDepartment of Rheumatology, Toulouse University Hospital and University Toulouse III, Toulouse, France.
Richard KochDepartment of Rheumatology, Toulouse University Hospital and University Toulouse III, Toulouse, France.
Laurent ZabranieckiDepartment of Rheumatology, Toulouse University Hospital and University Toulouse III, Toulouse, France.
Bénédicte JamardDepartment of Rheumatology, Toulouse University Hospital and University Toulouse III, Toulouse, France.
Guillaume CoutureDepartment of Rheumatology, Toulouse University Hospital and University Toulouse III, Toulouse, France.
Jean Bernard RuidavetsDepartment of Epidemiology, INSERM UMR 1027, Toulouse University Hospital, Toulouse, France.
Jean FerrieresDepartment of Cardiology, Toulouse University Hospital and University Toulouse III, Toulouse, France.
Adeline Ruyssen-WitrandDepartment of Rheumatology, Toulouse University Hospital and University Toulouse III, Toulouse, France.
Arnaud ConstantinDepartment of Rheumatology, Toulouse University Hospital and University Toulouse III, Toulouse, France.
Université Fédérale de Toulouse Midi-Pyrénées · FRUniversité Toulouse III - Paul Sabatier · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Psoriatic arthritis (PsA) is associated with increased cardiovascular morbidity and mortality. The aims of our real-life study were to compare the prevalence of cardiovascular risk factors (CVRFs) and cardiovascular events (CVEs) among patients with PsA with a control population, to evaluate the impact of correcting factors in equations that assess cardiovascular risk (CVR) in PsA, and to determine the percentage of patients who reach the LDLc target as indicated by the European guidelines. Methods: In this observational cross-sectional monocentric case-control study, we used a standardized procedure to systematically assess patients with PsA aged 25-85 years who met the Classification for Psoriatic Arthritis (CASPAR) criteria. Controls were extracted from the MOnitoring NAtionaL du rISque Artériel (MONALISA) study. We compared the prevalence of CVRFs, CVEs, the CVR, and the percentage of patients reaching recommended LDLc target in both populations. The CVR was first assessed using SCORE and QRISK2 equations. Then, the SCORE equation was corrected by applying a 1.5 multiplication factor, as recommended by EULAR for rheumatoid arthritis (SCORE-PsA), and the QRISK2 was corrected using the "rheumatoid arthritis" item (QRISK2-PsA). Results: A total of 207 PsA and 414 controls were included. CVRFs and CVEs were more frequent in the PsA group. After controlling for age and gender, atherothrombotic disease was increased in the PsA population (SCORE Conclusion: In real-life, patients with PsA have a higher prevalence of CVRFs, as well as a higher prevalence of CVEs compared to the general population. The CVR is higher in the PsA population than in the controls either using the SCORE and QRISK2 equations or using the corrected SCORE- PsA and QRISK2-PsA equations.

Indexed as

cardiovascular eventscardiovascular riskdyslipidaemiapsoriatic arthritisstatins

Identifiers

PMID35665348
PMCPMC9160333
OpenAlexW4280635218

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.