Evidence map›Paper›PMID 35665341›Full record

ArticleFrontiers in medicine2022

Biometric and Structural Ocular Manifestations of Anterior Megalophthalmos.

Tian-Hui Chen, Ze-Xu Chen, Min Zhang, Jia-Hui Chen, Li-Na Lan, Yongxiang Jiang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Tian-Hui ChenDepartment of Ophthalmology and Vision Science, Eye & ENT Hospital of Fudan University, Shanghai, China.
Ze-Xu ChenDepartment of Ophthalmology and Vision Science, Eye & ENT Hospital of Fudan University, Shanghai, China.
Min ZhangDepartment of Ophthalmology and Vision Science, Eye & ENT Hospital of Fudan University, Shanghai, China.
Jia-Hui ChenDepartment of Ophthalmology and Vision Science, Eye & ENT Hospital of Fudan University, Shanghai, China.
Li-Na LanDepartment of Ophthalmology and Vision Science, Eye & ENT Hospital of Fudan University, Shanghai, China.
Yongxiang JiangDepartment of Ophthalmology and Vision Science, Eye & ENT Hospital of Fudan University, Shanghai, China.
Sun Yat-sen University · CNEye & ENT Hospital of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aim of this study was to examine the biometric ocular manifestations and structural ocular features of anterior megalophthalmos (AM). Methods: Fifteen patients with AM (30 eyes) from the Eye & ENT Hospital of Fudan University were included. The age-matched control group consisted of 30 participants (30 eyes) who underwent Pentacam HR and IOLMaster 700 measurements for one normal eye. Data on demographics, biometric manifestations, and genotypes were carefully compared. Results: A total of 15 patients with AM and 30 control patients were enrolled. There were no differences in age (37.27 ± 19.1 vs. 31.43 ± 19.69 years, Conclusion: The results of this cohort study conclude the biometric and structural ocular manifestations in Chinese cohorts. Posterior iris bowing (66.67%) and lens subluxation (73.33%) are the most characteristic findings in patients with AM with anatomical abnormalities of megalocornea and a deep anterior chamber, although corneal biometric manifestations of AM included flatter cornea and lower total corneal astigmatism. The knowledge of ocular manifestations of AM is important for diagnosis and preparation for the operation in advance to avoid intraoperative and postoperative complications. Significant differences were found in the anterior chamber and WTW values between the Pentacam HR and IOLMaster 700. Thus, we suggest that various examinations should be carefully considered before determining an AM diagnosis.

Indexed as

anterior megalophthalmoscataractlens subluxationmegalocorneaocular manifestations

Identifiers

PMID35665341
PMCPMC9160329
OpenAlexW4280594972

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.