Evidence map›Paper›PMID 35665328›Full record

ArticleFrontiers in medicine2022

Contrast Sensitivity Deficits and Its Structural Correlates in Fuchs Uveitis Syndrome.

Fang-Yue Zhou, Yi-Sha Li, Xingneng Guo, Xiutong Shi, Ke Wu, Jing-Wei Zheng, Xia-Xin Li, Jiaqing Wu, Ruru Liu, Ma-Li Dai and 4 more

Abstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Fang-Yue ZhouSchool of Ophthalmology & Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Yi-Sha LiSchool of Ophthalmology & Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Xingneng GuoSchool of Ophthalmology & Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Xiutong ShiSchool of Optometry, Tianjin Vocational Institute, Tianjin, China.
Ke WuSchool of Ophthalmology & Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Jing-Wei ZhengSchool of Ophthalmology & Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Xia-Xin LiSchool of Ophthalmology & Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Jiaqing WuSchool of Ophthalmology & Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Ruru LiuSchool of Ophthalmology & Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Ma-Li DaiSchool of Ophthalmology & Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Xiu-Feng HuangThe Second Affiliated Hospital, Wenzhou Medical University, Wenzhou, China.
Fang HouSchool of Ophthalmology & Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Dan LinSchool of Ophthalmology & Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Yu-Qin WangSchool of Ophthalmology & Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the deficits in contrast sensitivity in patients with Fuchs uveitis syndrome (FUS) and to explore the potential relationship between contrast sensitivity and ocular structure. Methods: In this prospective study, 25 patients with FUS and 30 healthy volunteers were recruited. Eyes were divided into three groups: FUS-affected eyes (AE), fellow eyes (FE), and healthy eyes. The contrast sensitivity function (CSF) of all participants was evaluated using the quick CSF (qCSF) method. Fundus photographs were collected for the analysis of refractive media, and vascular density (VD) was assessed using optical coherence tomography angiography (OCTA). Data were analyzed and compared using the generalized estimating equation (GEE). Results: The CSF of AE was significantly lower than that of FE and controls, while no significant difference was observed between FE and controls. Contrast sensitivity was negatively correlated with the grade of haze. No significant correlation was found between visual function and VDs in FUS eyes. Conclusions: We found that the CSF of FUS-affected eyes was significantly reduced, and the visual impairment was predominantly caused by the refractive media turbidity.

Indexed as

contrast sensitivityFuchs uveitis syndromegrading of hazeoptical coherence tomography angiographyqCSF

Identifiers

PMID35665328
PMCPMC9160426

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.