ArticleFrontiers in plant science2022
An Integrated Metabolome and Transcriptome Analysis Reveal the Regulation Mechanisms of Flavonoid Biosynthesis in a Purple Tea Plant Cultivar.
Article in Frontiers in plant science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23 citing papers in PubMed, 51 citations in OpenAlex.
- Effect of roasting intensity on sensory quality and chemical composition of Zijuan oolong tea.Food chemistry: X · 2026Article
- Integrated Transcriptomic and Biochemical Profiling Reveals the Regulatory Mechanism of Light Intensity-Induced Anthocyanin Biosynthesis in a Purple-Leaf Tea Cultivar.Plants (Basel, Switzerland) · 2026Article
- Progressive salinity drives flavonoid branch reprogramming in Anoectochilus roxburghii.BMC plant biology · 2026Article
- Catechin-Folate nano-niosomes from Osbeckia parvifolia Arn. induce apoptotic cell death in Ovarian cancer.Scientific reports · 2026Article
- Integrated metabolomic and transcriptomic analyses provide new perspectives into the discoloration of hawk tea tender leaves.BMC plant biology · 2026Article
- Integrated Metabolome and Transcriptome Analysis in Ammi majus L. Revealed Candidate Genes of Furanocoumarins Pathway.Biochemical genetics · 2026Article
- A review of flavonoids at the crossroads of plant defense: integrating biotic and abiotic stress tolerance through AI- and CRISPR/Cas-guided metabolic reprogramming.Frontiers in plant science · 2026Review
- Tissue-specific biosynthesis and spatial distribution of xanthones in Garcinia oblongifolia revealed by integrated metabolomic and full-length transcriptomic analyses.BMC genomics · 2025Article
- Integrated Multi-Omics Approaches Provide Novel Insights into the Mechanisms Underlying Signature Flavor Development in Mulberry Fruits.Foods (Basel, Switzerland) · 2025Article
- Network-based identification of hub transcription factors associated with benzylisoquinoline alkaloid biosynthesis inBiochemistry and biophysics reports · 2025Article
- Comprehensive transcriptomics and metabolomics reveal the coloring mechanism of purple Camellia tachangensis.BMC plant biology · 2025Article
- Multi-Omics Analysis Revealed the Accumulation of Flavonoids and Shift of Fungal Community Structure Caused by Tea Grafting (Plants (Basel, Switzerland) · 2025Article
- Integrated metabolomic and transcriptomic analysis of anthocyanin metabolism in wheat pericarp.BMC genomic data · 2025Article
- Deciphering the anthocyanin metabolism gene network in tea plant (Camellia sinensis) through structural equation modeling.BMC genomics · 2024Article
- A functional study reveals CsNAC086 regulated the biosynthesis of flavonols in Camellia sinensis.Planta · 2024Article
- Integrated transcriptomic and WGCNA analyses reveal candidate genes regulating mainly flavonoid biosynthesis in Litsea coreana var. sinensis.BMC plant biology · 2024Article
- Multi-Omics Research Accelerates the Clarification of the Formation Mechanism and the Influence of Leaf Color Variation in Tea (Plants (Basel, Switzerland) · 2024Review
- An integrated metabolomic and transcriptomic analysis reveals the dynamic changes of key metabolites and flavor formation over Tieguanyin oolong tea production.Food chemistry: X · 2023Article
- Gene mining and genomics-assisted breeding empowered by the pangenome of tea plant Camellia sinensis.Nature plants · 2023Article
- Identification of R2R3-MYB family in blueberry and its potential involvement of anthocyanin biosynthesis in fruits.BMC genomics · 2023Article
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purple tea plant cultivars, enrich with flavonoids and anthocyanins, are valuable materials for manufacturing tea with unique color and flavor. Researchers found that 'Zijuan' leaves changed from purple to green mainly caused by the decreased flavonoids and anthocyanins concentrations. The mechanism of flavonoids and anthocyanin biosynthesis has been studied in many purple tea plant cultivars and the key genes which regulated the biosynthesis of flavonoid and anthocyanins in different purple tea plant cultivars were quite different. Also, the molecular regulation mechanism underlying the flavonoids and anthocyanins biosynthesis during leaves development and color changes is less-thoroughly understood. In this study, an integrative analysis of transcriptome and metabolome was performed on the purple leaves and green leaves of 'Zijuan' tea plant to reveal the regulatory networks correlated to flavonoid biosynthesis and to identify key regulatory genes. Our results indicated that the 'Zijuan' new shoots leaves were purple might be due to the copigmentation of quercetin and kaempferol derivatives. In 'Zijuan' tea plant cultivar, flavonoids metabolites concentrations in purple leaves and green leaves were significantly influenced by the genes involved in flavonoid biosynthesis, transcriptional regulation, transport, and hormone response. Transcription factors including NAC008, MYB23, and bHLH96 and transporters such as ABC transporter I might be responsible for the flavonoid and anthocyanins accumulation in purple leaves. This study provides a new insight into the metabolism and molecular mechanisms underlying flavonoid and anthocyanin biosynthesis in tea plant.
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