Evidence map›Paper›PMID 35664846›Full record

ArticleFrontiers in veterinary science2022

Irradiated Non-replicative Lactic Acid Bacteria Preserve Metabolic Activity While Exhibiting Diverse Immune Modulation.

Luca Porfiri, Johanna Burtscher, Richard T Kangethe, Doris Verhovsek, Giovanni Cattoli, Konrad J Domig, Viskam Wijewardana

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Review
  3. Crosstalk BetweenInsects · 2026
    Article
  4. Review
  5. Genomic Insights and Inactivation Strategies forFoods (Basel, Switzerland) · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Emerging Nonthermal Technologies for the Production of Postbiotics.Comprehensive reviews in food science and food safety · 2025
    Review
  10. Review
  11. A screening setup to streamlineMaterials today. Bio · 2025
    Article
  12. Article
  13. Review
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Luca PorfiriAnimal Production and Health Section, Joint Food and Agriculture Organization (FAO)/International Atomic Energy Agency (IAEA) Centre of Nuclear Techniques in Food and Agriculture, International Atomic Energy Agency, Vienna, Austria.
Johanna BurtscherDepartment of Food Science and Technology, Institute of Food Science, University of Natural Resources and Life Sciences, Vienna, Austria.
Richard T KangetheAnimal Production and Health Section, Joint Food and Agriculture Organization (FAO)/International Atomic Energy Agency (IAEA) Centre of Nuclear Techniques in Food and Agriculture, International Atomic Energy Agency, Vienna, Austria.
Doris VerhovsekVetFarm Medau, University of Veterinary Medicine Vienna, Berndorf, Austria.
Giovanni CattoliAnimal Production and Health Section, Joint Food and Agriculture Organization (FAO)/International Atomic Energy Agency (IAEA) Centre of Nuclear Techniques in Food and Agriculture, International Atomic Energy Agency, Vienna, Austria.
Konrad J DomigDepartment of Food Science and Technology, Institute of Food Science, University of Natural Resources and Life Sciences, Vienna, Austria.
Viskam WijewardanaAnimal Production and Health Section, Joint Food and Agriculture Organization (FAO)/International Atomic Energy Agency (IAEA) Centre of Nuclear Techniques in Food and Agriculture, International Atomic Energy Agency, Vienna, Austria.
International Atomic Energy Agency · ATBOKU University · ATUniversity of Veterinary Medicine Vienna · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the recent years, safety concerns regarding the administration of probiotics led to an increased interest in developing inactivated probiotics, also called "paraprobiotics". Gamma irradiation represents a promising tool that can be used to produce safe paraprobiotics by inhibiting replication while preserving the structure, the metabolic activity, and the immunogenicity of bacteria. In this study, we evaluated the ability of four strains of lactic acid bacteria (LAB:

Indexed as

gamma irradiationimmune modulationlactic acid bacteriametabolic activityvaccine adjuvant

Identifiers

PMID35664846
PMCPMC9158532
OpenAlexW4280541337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.