Evidence map›Paper›PMID 35664662›Full record

ArticleMicrofluidics and nanofluidics2019

3D hydrodynamic focusing in microscale channels formed with two photoresist layers.

Erik S Hamilton, Vahid Ganjalizadeh, Joel G Wright, William G Pitt, Holger Schmidt, Aaron R Hawkins

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microfluidics and nanofluidics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Greatly Enhanced Single Particle Fluorescence Detection Using High Refractive Index Liquid-Core Waveguides.IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Erik S HamiltonElectrical and Computer Engineering, Brigham Young University, 450 Engineering Building, Provo, UT 84602, USA.ORCID 0000-0001-8532-0836
Vahid GanjalizadehElectrical and Computer Engineering, University of California, Santa Cruz, 1156 High Street, Santa Cruz, CA 95064, USA.
Joel G WrightElectrical and Computer Engineering, Brigham Young University, 450 Engineering Building, Provo, UT 84602, USA.
William G PittChemical Engineering, Brigham Young University, 330 Engineering Building, Provo, UT 84602, USA.
Holger SchmidtElectrical and Computer Engineering, University of California, Santa Cruz, 1156 High Street, Santa Cruz, CA 95064, USA.
Aaron R HawkinsElectrical and Computer Engineering, Brigham Young University, 450 Engineering Building, Provo, UT 84602, USA.

Funding

Multiplexed, Non-Amplified, Nucleic Acid-Based Identification of Multidrug Resistant Pathogens Using an Integrated Optofluidic PlatformR01AI116989 · NIAID · BRIGHAM YOUNG UNIVERSITY · PI HAWKINS, AARON R., PITT, WILLIAM G · 2015 to 2019
$5.4M
NIAID NIH HHS R01 AI116989
6 · The paper itself

Abstract

3D hydrodynamic focusing was implemented with channel cross-section dimensions smaller than 10 μm. Microchannels were formed using sacrificial etching of two photoresist layers on a silicon wafer. The photoresist forms a plus-shaped prismatic focusing fluid junction which was coated with plasma-enhanced chemical-vapor-deposited oxide. Buffer fluid carried to the focusing junction envelopes an intersecting sample fluid, resulting in 3D focusing of the sample stream. The design requires four fluid ports and operates across a wide range of fluid velocities through pressure-driven flow. The focusing design was integrated with optical waveguides to interrogate fluorescing particles and confirm 3D focusing. Particle diffusion away from a focused stream was characterized.

Indexed as

3D hydrodynamic focusingLiquid-core waveguideMicroscale channelOptofluidic

Identifiers

PMID35664662
PMCPMC9162057

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.