ArticleACS omega2022
Backscattering-Based Discrimination of Microparticles Using an Optofluidic Multiangle Scattering Chip.
Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed, 2 citations in OpenAlex.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this research, we designed and fabricated an optofluidic chip for the detection and differentiation of single particles via the combination of backscattered (BSC) and forward-scattered (FSC) or side-scattered (SSC) light intensity. The high sensitivity of BSC light to the refractive index of the particles enabled an effective approach for the differentiation of individual particles based on the type of material. By recording BSC as well as FSC and SSC light intensities from single particles, transiting through the illumination zone in a microfluidic channel, the size and type of material could be detected simultaneously. The analysis of model samples of polystyrene (PS), as a primary microplastic particle, and silica microspheres showed substantially higher BSC signal values of PS because of a larger refractive index compared to the silica. The scatter plots correlating contributions of BSC (FSC-BSC and SSC-BSC) allowed a clear differentiation of PS and silica particles. To demonstrate the great potential of this methodology, two "real-life" samples containing different types of particles were tested as application examples. Commercial toothpaste and peeling gel products, as primary sources of microplastics into effluents, were analyzed via the optofluidic chip and compared to results from scanning electron microscopy. The scattering analysis of the complex samples enabled the detection and simultaneous differentiation of particles such as microplastics according to their differences in the refractive index via distinctive areas of high and low BSC signal values. Hence, the contribution of BSC light measurements in multiangle scattering of single particles realized in an optofluidic chip opens the way for the discrimination of single particles in a liquid medium in manifold fields of application ranging from environmental monitoring to cosmetics.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.