ArticleWorld journal of diabetes2022
Changes and significance of retinal blood oxygen saturation and oxidative stress indexes in patients with diabetic retinopathy.
Article in World journal of diabetes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Comparative evaluation of oxidative stress biomarkers F2-isoprostanes and 8-OHdG in Parkinson's disease and Type 2 Diabetes Mellitus: a systematic review and meta-analysis of human studies.Annals of medicine · 2026Pooled it
- Development of a multispectral imaging apparatus for cost-effective fundus disease detection.Biomedical optics express · 2025Article
- Evaluation of macular retinal oximetry across different levels of diabetic retinopathy: a cross sectional study.BMC ophthalmology · 2025Article
- Correlation Between Retinal Vascular Oxygen Saturation, Red Blood Cell Parameters and Hemorheology Parameters in Healthy Adults.Clinical optometry · 2025Article
- Diagnostic and Prognostic Predictive Value of Serum Selenium and Redox Biomarkers in Retinal Vein Occlusion.International journal of general medicine · 2025Article
- Down-regulation of histone deacetylase 7 reduces biological activities of retinal microvascular endothelial cells under high glucose condition and related mechanism.International journal of ophthalmology · 2023Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiabetic retinopathy (DR) is a diabetic complication that can severely affect the patients' vision, eventually leading to blindness. DR is the most important manifestation of diabetic micro-vasculopathy and is mainly related to the course of diabetes and the degree of blood glucose control, while the age of diabetes onset, sex, and type of diabetes have little influence on it.
aimTo explore the changes in blood oxygen saturation and oxidative stress indices of retinal vessels in patients with DR.
methodsIn total, 94 patients (94 eyes) with DR (DR group) diagnosed at Jianyang people's Hospital between March 2019 and June 2020, and 100 volunteers (100 eyes) (control group) without eye diseases, were included in this study. Arterial and venous blood oxygen saturation, retinal arteriovenous vessel diameter, and serum oxidative stress indicators in the two groups were compared. Based on the stage of the disease, the DR group was divided into the simple DR and proliferative DR groups for stratified analysis.
resultsThe oxygen saturation of the retinal vessels in the DR group was significantly higher than that in the control group (
conclusionIncreased blood oxygen saturation of retinal arteries and veins and increased oxidative stress damage in patients with DR may be associated with decreased retinal capillary permeability and arterial oxygen dispersion, possibly reflecting the patient's condition.
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