ArticleFrontiers in psychiatry2022
Internalized and Perceived Stigma and Depression in Pulmonary Tuberculosis: Do They Explain the Relationship Between Drug Sensitivity Status and Adherence?
Article in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 21 citations in OpenAlex.
- Stigma and depression among patients with tuberculosis in Khyber Pakhtunkhwa Pakistan: a cross-sectional study.BMC public health · 2026Article
- Settings, characteristics, and experiences of stigma among people with tuberculosis in Kenya: National survey results.PLOS global public health · 2026Article
- Latent transition analysis of stigma and its association with treatment adherence in pulmonary tuberculosis patients during anti-tuberculosis therapy.Frontiers in public health · 2026Article
- Enacted and internalized stigma as predictors of successful treatment outcome among newly diagnosed tuberculosis patients in Gauteng, South Africa.Frontiers in psychology · 2026Article
- Prevalence and predictors of depression in tuberculosis patients in india: a systematic review and meta-analysis.Discover mental health · 2025Review
- TB stigma in India: A narrative review of types of stigma, gender differences, and potential interventions.PLOS global public health · 2025Review
- Understanding stigma: The experiences of people with drug-sensitive pulmonary tuberculosis in Rawalpindi, Pakistan.PloS one · 2025Article
- Drug-resistant tuberculosis: a persistent global health concern.Nature reviews. Microbiology · 2024Review
- An adapted scale to measure perceived TB and HIV stigma during household contact investigation.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2024Article
- Stigma, depression, and quality of life among people with pulmonary tuberculosis diagnosed through active and passive case finding in Nepal: a prospective cohort study.BMC global and public health · 2024Article
- The effect of the peer support intervention on internalized stigma among Thai patients with tuberculosis: A repeated measures design.Belitung nursing journal · 2024Article
- The Chinese version of the tendency to stigmatize epidemic diseases scale: a translation and validation study.Frontiers in psychiatry · 2024Article
- Perceived stigma among people with TB and household contacts.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2023Article
- Editorial: Community series in mental health promotion and protection, volume II.Frontiers in psychiatry · 2023Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Adherence to medication for tuberculosis (TB) has been found to be deleteriously affected by psychosocial issues, including internalized and perceived stigma (IPS) and depression, usually resulting in the emergence of multidrug-resistant TB (MDR-TB). The objective of the study was to find the prevalence of depression among patients receiving treatment for pulmonary TB, and how stigma and depression affect the relationship between drug sensitivity status (DSS) and treatment adherence. Method: It was a cross-sectional observational study conducted between January 2019 and July 2020 in two centers in Sikkim, India. The Patient Health Questionnaire-9 (PHQ-9), Internalized Social Stigma Scale (ISSS), and Tuberculosis Medication Adherence Scale were used to assess depression, IPS, and medication adherence, respectively. A path analysis was performed with DSS, treatment adherence, IPS, and depression. Education in years was included in the model as it was significantly correlated with IPS. Results: A total of 71 patients who were on drug-sensitive TB (DS-TB) regimen ( Conclusion: We found an important relationship between different psychosocial factors which may affect treatment adherence. Patients who have higher IPS are more likely to develop depression which negatively affect adherence. Patients on the MDR-TB regimen have higher stigma. There is an urgent need to integrate mental health services with TB Control Programs.
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