Evidence map›Paper›PMID 35664282›Full record

ArticleClinical kidney journal2022

New-onset anemia and associated risk of ESKD and death in non-dialysis CKD patients: a multicohort observational study.

Roberto Minutolo, Michele Provenzano, Paolo Chiodini, Silvio Borrelli, Carlo Garofalo, Michele Andreucci, Maria Elena Liberti, Vincenzo Bellizzi, Giuseppe Conte, Luca De Nicola and 1 more

Open access · goldAbstract read
In one paragraph

Article in Clinical kidney journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
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  12. Observational
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  15. Global & regional health technology assessment
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Roberto MinutoloNephrology Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.ORCID https://orcid.org/0000-0001-5686-2089
Michele ProvenzanoNephrology Unit, Department of Health Sciences, "Magna Graecia," University of Catanzaro, Catanzaro, Italy.
Paolo ChiodiniMedical Statistics Unit, University of Campania "Luigi Vanvitelli," Naples, Italy.
Silvio BorrelliNephrology Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
Carlo GarofaloNephrology Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
Michele AndreucciNephrology Unit, Department of Health Sciences, "Magna Graecia," University of Catanzaro, Catanzaro, Italy.
Maria Elena LibertiNephrology Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
Vincenzo BellizziNephrology Unit, University Hospital "San Giovanni di Dio e Ruggi d'Aragona," Salerno, Italy.
Giuseppe ConteNephrology Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.
Luca De NicolaNephrology Unit, University of Campania "Luigi Vanvitelli", Naples, Italy.ORCID https://orcid.org/0000-0001-8532-0182
Collaborative Study Group on the Conservative Treatment of CKD of the Italian Society of Nephrology
University of Campania "Luigi Vanvitelli" · ITOspedali Riuniti San Giovanni di Dio e Ruggi d'Aragona · ITMagna Graecia University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Anemia is a common complication of chronic kidney disease (CKD), but its incidence in nephrology settings is poorly investigated. Similarly, the risks of adverse outcomes associated with new-onset anemia are not known. Methods: We performed a pooled analysis of three observational cohort studies including 1031 non-anemic CKD patients with eGFR <60 mL/min/1.73 m Results: The mean age was 63 ± 14 years, 60% were men and 20% had diabetes. The mean estimated glomerular filtration rate (eGFR) was 37 ± 13 mL/min/1.73 m Conclusions: New-onset anemia is frequent, particularly in patients with more severe renal damage and in those with diabetes mellitus. The occurrence of anemia, even of a mild degree, is associated with mortality risk and faster progression towards ESKD.

Indexed as

anemiaepidemiologyESKDnon-dialysis CKD

Identifiers

PMID35664282
PMCPMC9155211
OpenAlexW4206558510

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.