Evidence map›Paper›PMID 35664224›Full record

ArticleComputational and structural biotechnology journal2022

MIAOME: Human microbiome affect the host epigenome.

Lidan Wang, Wei Zhang, Xianglu Wu, Xiao Liang, Lijie Cao, Jincheng Zhai, Yiyang Yang, Qiuxiao Chen, Hongqing Liu, Jun Zhang and 3 more

Open access · goldAbstract read
In one paragraph

Article in Computational and structural biotechnology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Can Postbiotics Represent a New Strategy for NEC?Advances in experimental medicine and biology · 2024
    Review
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Lidan WangSchool of Basic Medicine, Chongqing Medical University, Chongqing 400016, China.
Wei ZhangCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Xianglu WuJoint International Research Laboratory of Reproductive and Development, Department of Reproductive Biology, School of Public Health, Chongqing Medical University, Chongqing 400016, China.
Xiao LiangSchool of Basic Medicine, Chongqing Medical University, Chongqing 400016, China.
Lijie CaoSchool of Basic Medicine, Chongqing Medical University, Chongqing 400016, China.
Jincheng ZhaiSchool of Basic Medicine, Chongqing Medical University, Chongqing 400016, China.
Yiyang YangSchool of Basic Medicine, Chongqing Medical University, Chongqing 400016, China.
Qiuxiao ChenSchool of Basic Medicine, Chongqing Medical University, Chongqing 400016, China.
Hongqing LiuSchool of Basic Medicine, Chongqing Medical University, Chongqing 400016, China.
Jun ZhangSchool of Basic Medicine, Chongqing Medical University, Chongqing 400016, China.
Yubin DingJoint International Research Laboratory of Reproductive and Development, Department of Reproductive Biology, School of Public Health, Chongqing Medical University, Chongqing 400016, China.
Feng ZhuCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Jing TangSchool of Basic Medicine, Chongqing Medical University, Chongqing 400016, China.
Chongqing Medical University · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Besides the genetic factors having tremendous influences on the regulations of the epigenome, the microenvironmental factors have recently gained extensive attention for their roles in affecting the host epigenome. There are three major types of microenvironmental factors: microbiota-derived metabolites (MDM), microbiota-derived components (MDC) and microbiota-secreted proteins (MSP). These factors can regulate host physiology by modifying host gene expression through the three highly interconnected epigenetic mechanisms (

Indexed as

EM, Epigenetic moleculeEpigenetic modificationHDACs, histone deacetylasesHost epigenomeHuman microbiomeLPS, lipopolysaccharideMDC, microbiota-derived componentsMDM, microbiota-derived metabolitesMicrobiota-derived metabolitesMicrobiota-secreted proteinsmiRNA, microRNAMSP, microbiota-secreted proteinsncRNAs, non-coding RNAs

Identifiers

PMID35664224
PMCPMC9136154
OpenAlexW4280593322

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.