Evidence map›Paper›PMID 35663920›Full record

ArticleClinical & translational immunology2022

Increased amphiregulin expression by CD4

Siddharth Sankar Singh, Shashi Bhushan Chauhan, Susanna Ss Ng, Dillon Corvino, Fabian de Labastida Rivera, Jessica A Engel, Nic Waddell, Pamela Mukhopadhay, Rebecca L Johnston, Lambros T Koufariotis and 5 more

Open access · goldAbstract read
In one paragraph

Article in Clinical & translational immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Cytotoxic CD4Parasite immunology · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Immune response to viscerotropicFrontiers in immunology · 2024
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 4 countries.

Siddharth Sankar SinghDepartment of Medicine, Institute of Medical Sciences Banaras Hindu University Varanasi India.
Shashi Bhushan ChauhanDepartment of Medicine, Institute of Medical Sciences Banaras Hindu University Varanasi India.
Susanna Ss NgQIMR Berghofer Medical Research Institute Brisbane Australia.
Dillon CorvinoQIMR Berghofer Medical Research Institute Brisbane Australia.ORCID https://orcid.org/0000-0003-0683-1369
Fabian de Labastida RiveraQIMR Berghofer Medical Research Institute Brisbane Australia.
Jessica A EngelQIMR Berghofer Medical Research Institute Brisbane Australia.ORCID https://orcid.org/0000-0001-6175-1797
Nic WaddellDepartment of Medicine, Institute of Medical Sciences Banaras Hindu University Varanasi India.
Pamela MukhopadhayDepartment of Medicine, Institute of Medical Sciences Banaras Hindu University Varanasi India.
Rebecca L JohnstonDepartment of Medicine, Institute of Medical Sciences Banaras Hindu University Varanasi India.
Lambros T KoufariotisDepartment of Medicine, Institute of Medical Sciences Banaras Hindu University Varanasi India.
Susanne NylenDepartment of Microbiology, Tumor and Cell Biology Karolinska Institute Stockholm Sweden.
Om Prakash SinghDepartment of Biochemistry Banaras Hindu University Varanasi India.
Christian R EngwerdaQIMR Berghofer Medical Research Institute Brisbane Australia.
Rajiv KumarCentre of Experimental Medicine and Surgery Institute of Medical Sciences Banaras Hindu University Varanasi India.ORCID https://orcid.org/0000-0003-2338-1494
Shyam SundarDepartment of Medicine, Institute of Medical Sciences Banaras Hindu University Varanasi India.
QIMR Berghofer Medical Research Institute · AUInstitute of Medical Sciences · INUniversity of Bonn · DEBanaras Hindu University · INKarolinska Institutet · SE

Funding

Visceral Leishmaniasis in Bihar State, IndiaP50AI074321 · NIAID · BANARAS HINDU UNIVERSITY · PI SUNDAR, SHYAM · 2007 to 2016
$6.4M
Visceral Leishmaniasis in Bihar State, IndiaU19AI074321 · NIAID · BANARAS HINDU UNIVERSITY · PI SUNDAR, SHYAM · 2017 to 2021
$2.8M
NIAID NIH HHS P50 AI074321NIAID NIH HHS U19 AI074321
6 · The paper itself

Abstract

Objectives: There is an urgent need to be able to identify individuals with asymptomatic Methods: CD4 Results: Amphiregulin (AREG) was identified as a distinguishing gene product in CD4 Conclusion: Increased Treg cell

Indexed as

amphiregulinCD4+ T cellLeishmania donovaniregulatory T cellvisceral leishmaniasis

Identifiers

PMID35663920
PMCPMC9136704
OpenAlexW4285193038

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.