Evidence map›Paper›PMID 35663451›Full record

ArticleInternational journal of cardiology. Heart & vasculature2022

Impact of undiagnosed obstructive sleep apnea on atrial fibrillation recurrence following catheter ablation (OSA-AF study).

John de Heide, Danielle B M Kock-Cordeiro, Rohit E Bhagwandien, Mark G Hoogendijk, Koen C van der Meer, Sip A Wijchers, Tamas Szili-Torok, Felix Zijlstra, Mattie J Lenzen, Sing-Chien Yap

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07444372 (Start CPAP Therapy in Obstructive Sleep Apnea Patients After Atrial Fibrillation Ablation), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07444372 narecruitingnot on this mapstarted 2026, after this paper: background citation

Start CPAP Therapy in Obstructive Sleep Apnea Patients After Atrial Fibrillation Ablation: A Multicenter, Open-label, Randomized Clinical Trial

TypeinterventionalSponsorBeijing Anzhen HospitalRan2026 to 2029Enrolled658ConditionsObstructive Sleep Apnea, Sleep Disorder (Disorder), Atrial Fibrillation (AF), Sleep Disordered Breathing (SDB)ArmsContinuous Positive Airway Pressure (CPAP), Usual Care
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  9. Recent highlights from theInternational journal of cardiology. Heart & vasculature · 2024
    Article
  10. Global burden of atrial fibrillation/atrial flutter and its attributable risk factors from 1990 to 2021.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  11. Article
  12. Article
  13. Sleeping Beauty unravelled - Detection of sleep apnoea in patients with atrial fibrillation.International journal of cardiology. Heart & vasculature · 2023
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

John de HeideDepartment of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Danielle B M Kock-CordeiroDepartment of Intensive Care/Home Mechanical Ventilation and Pulmonology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Rohit E BhagwandienDepartment of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Mark G HoogendijkDepartment of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Koen C van der MeerDepartment of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Sip A WijchersDepartment of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Tamas Szili-TorokDepartment of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Felix ZijlstraDepartment of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Mattie J LenzenDepartment of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Sing-Chien YapDepartment of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Erasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Sleep-disordered breathing (SDB) may hamper the outcome of catheter ablation of atrial fibrillation (AF). However, SDB is underdiagnosed in clinical practice and the relevancy of undiagnosed SDB on the outcome of catheter ablation is unclear. Objective: To evaluate if undiagnosed SDB has an impact on AF recurrence after catheter ablation. Methods: In this single-center cohort study we enrolled patients who had a catheter ablation of AF 12 to 18 months prior to enrolment. Patients with diagnosed SDB at the time of catheter ablation were excluded. Enrolled patients underwent screening using WatchPAT (WP). SDB was defined as an apnea-hypopnea index (AHI) ≥ 15. Results: A total of 164 patients were screened for eligibility. After exclusion of patients with previously diagnosed SDB (n = 30), 104 of 134 eligible patients were enrolled and underwent SDB screening. The median AHI was 11.5 (interquartile range 6.8-21.9) and 39 patients (38%) had SDB which was undiagnosed during the first year after ablation. AF recurrence in the first year after catheter ablation occurred in 40 patients (38%). The risk of AF recurrence was higher in the group with undiagnosed SDB in comparison to those without SDB (51% versus 31%, P = 0.04). Interestingly, the prevalence of AF recurrence was similar between patients with previously diagnosed and undiagnosed SDB (51% versus 50%, P = 0.92). Conclusion: A significant proportion of patients undergoing catheter ablation of AF have undiagnosed SDB which is associated with a twofold higher risk of AF recurrence. SDB screening may improve patient counselling regarding the efficacy of catheter ablation.

Indexed as

Atrial fibrillationCatheter ablationObstructive sleep apnea

Identifiers

PMID35663451
PMCPMC9157450
OpenAlexW4220902483

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.