Evidence map›Paper›PMID 35663386›Full record

ArticleFrontiers in cell and developmental biology2022

Inner Nuclear Membrane Protein, SUN1, is Required for Cytoskeletal Force Generation and Focal Adhesion Maturation.

Nanami Ueda, Masashi Maekawa, Tsubasa S Matsui, Shinji Deguchi, Tomoyo Takata, Jun Katahira, Shigeki Higashiyama, Miki Hieda

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Beyond DNA damage: 3D tumor models and the integrin mechanobiology of radioresistance.Journal of experimental & clinical cancer research : CR · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Nanami UedaDepartment of Medical Technology, Ehime Prefectural University of Health Sciences, Tobe, Japan.
Masashi MaekawaDivision of Cell Growth and Tumor Regulation, Proteo-Science Center (PROS), Ehime University, Matsuyama, Japan.
Tsubasa S MatsuiDivision of Bioengineering, Osaka University, Toyonaka, Japan.
Shinji DeguchiDivision of Bioengineering, Osaka University, Toyonaka, Japan.
Tomoyo TakataDepartment of Medical Technology, Ehime Prefectural University of Health Sciences, Tobe, Japan.
Jun KatahiraDepartment of Veterinary Sciences, Osaka Prefecture University, Sakai, Japan.
Shigeki HigashiyamaDivision of Cell Growth and Tumor Regulation, Proteo-Science Center (PROS), Ehime University, Matsuyama, Japan.
Miki HiedaDepartment of Medical Technology, Ehime Prefectural University of Health Sciences, Tobe, Japan.
Ehime Prefectural University of Health Science · JPOsaka University · JPKeio University · JPOsaka Medical Center for Cancer and Cardiovascular Diseases · JPOsaka Prefecture University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The linker of nucleoskeleton and cytoskeleton (LINC) complex is composed of the inner nuclear membrane-spanning SUN proteins and the outer nuclear membrane-spanning nesprin proteins. The LINC complex physically connects the nucleus and plasma membrane

Indexed as

actin cytoskeletonfocal adhesionintegrin β1LINC complexSUN proteinstraction force

Identifiers

PMID35663386
PMCPMC9157646
OpenAlexW4280640537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.