Evidence map›Paper›PMID 35663235›Full record

ArticleInternational journal of analytical chemistry2022

Pharmacokinetic Difference of Six Active Constituents of Huangqi Liuyi Decoction between Control and Diabetic Nephropathy Mouse Models.

Qun Wang, Ya Shi, Xingde Liu, Ting Liu, Yongjun Li, Xinli Song, Xiaolan Chen, Yang Jin, Wen Liu, Yonglin Wang and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of analytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Qun WangGuizhou University of Traditional Chinese Medicine, Huaxi University Town, Guiyang 550025, China.ORCID https://orcid.org/0000-0001-8579-9330
Ya ShiGuizhou University of Traditional Chinese Medicine, Huaxi University Town, Guiyang 550025, China.
Xingde LiuGuizhou University of Traditional Chinese Medicine, Huaxi University Town, Guiyang 550025, China.ORCID https://orcid.org/0000-0003-2140-0444
Ting LiuGuizhou Provincial Key Laboratory of Pharmaceutics, Guizhou Medical University, Beijing Road, Guiyang 550000, China.ORCID https://orcid.org/0000-0002-5824-3975
Yongjun LiGuizhou Provincial Key Laboratory of Pharmaceutics, Guizhou Medical University, Beijing Road, Guiyang 550000, China.
Xinli SongGuizhou University of Traditional Chinese Medicine, Huaxi University Town, Guiyang 550025, China.
Xiaolan ChenGuizhou University of Traditional Chinese Medicine, Huaxi University Town, Guiyang 550025, China.
Yang JinGuizhou Provincial Key Laboratory of Pharmaceutics, Guizhou Medical University, Beijing Road, Guiyang 550000, China.
Wen LiuGuizhou University of Traditional Chinese Medicine, Huaxi University Town, Guiyang 550025, China.ORCID https://orcid.org/0000-0002-4850-6719
Yonglin WangGuizhou Provincial Key Laboratory of Pharmaceutics, Guizhou Medical University, Beijing Road, Guiyang 550000, China.ORCID https://orcid.org/0000-0002-4663-1778
Zipeng GongGuizhou Provincial Key Laboratory of Pharmaceutics, Guizhou Medical University, Beijing Road, Guiyang 550000, China.ORCID https://orcid.org/0000-0003-2074-9476
Guizhou University · CNGuiyang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Huangqi Liuyi decoction is a famous traditional Chinese medicine (TCM) that has been widely used in China for the management of diabetes since the Song Dynasty. Today, it is commonly used for treating diabetic nephropathy (DN). Our previous experimental studies have suggested that the mixture HQD, containing astragalus saponin, astragalus flavone, astragalus polysaccharide, and glycyrrhetinic acid, could be used for the treatment of DN and to improve renal function. The objective of this study was to develop a sensitive and reliable high-performance liquid chromatography-tandem mass spectrometry method for simultaneous quantitation of astragaloside IV, calycosin-7-O-

Identifiers

PMID35663235
PMCPMC9159829
OpenAlexW4281551574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.