Evidence map›Paper›PMID 35663200›Full record

ArticleOxidative medicine and cellular longevity2022

Preventing Axonal Sodium Overload or Mitochondrial Calcium Uptake Protects Axonal Mitochondria from Oxidative Stress-Induced Alterations.

Rebecca Ulshöfer, Helena Bros, Anja Erika Hauser, Raluca Aura Niesner, Friedemann Paul, Bimala Malla, Carmen Infante-Duarte

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. pH-responsive CaCOiScience · 2026
    Article
  3. Mitochondrial pearling: membrane biophysics, CaFrontiers in cell and developmental biology · 2026
    Review
  4. Article
  5. Review
  6. Review
  7. Article
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  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Rebecca UlshöferExperimental and Clinical Research Center (ECRC), A Cooperation between Charité-Universitätsmedizin Berlin and Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany.
Helena BrosCharité-Universitätsmedizin Berlin, Institute for Medical Immunology, Augustenburger Platz 1, 13353 Berlin, Germany.
Anja Erika HauserCharité-Universitätsmedizin Berlin, Medizinische Klinik mit Schwerpunkt Rheumatologie und Klinische Immunologie, Charité Platz 1, 10117 Berlin, Germany.ORCID https://orcid.org/0000-0002-7725-9526
Raluca Aura NiesnerDeutsches Rheuma-Forschungszentrum, a Leibniz Institute, Charité Platz 1, 10117 Berlin, Germany.ORCID https://orcid.org/0000-0001-8969-5432
Friedemann PaulExperimental and Clinical Research Center (ECRC), A Cooperation between Charité-Universitätsmedizin Berlin and Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany.
Bimala Malla *Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt Universität zu Berlin and Berlin Institute of Health, 10117 Berlin, Germany.
Carmen Infante-Duarte *Experimental and Clinical Research Center (ECRC), A Cooperation between Charité-Universitätsmedizin Berlin and Max-Delbrück-Center for Molecular Medicine, 13125 Berlin, Germany.ORCID https://orcid.org/0000-0003-3005-351X
Max Delbrück Center · DECharité - Universitätsmedizin Berlin · DEFreie Universität Berlin · DEHumboldt-Universität zu Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In neuroinflammatory and neurodegenerative disorders such as multiple sclerosis, mitochondrial damage caused by oxidative stress is believed to contribute to neuroaxonal damage. Previously, we demonstrated that exposure to hydrogen peroxide (H

Indexed as

CalciumHydrogen PeroxideAdenosine TriphosphateAnimalsAxonsMiceMitochondriaOxidative StressSodiumAdenosine TriphosphateCalciumHydrogen PeroxideSodium

Identifiers

PMID35663200
PMCPMC9157283
OpenAlexW4285742087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.