Evidence map›Paper›PMID 35663190›Full record

ArticleJournal of molecular structure2022

Synthesis, crystal structure, and a molecular modeling approach to identify effective antiviral hydrazide derivative against the main protease of SARS-CoV-2.

Shaaban K Mohamed, Youness El Bakri, Dalia A Abdul, Sajjad Ahmad, Mustafa R Albayati, Chin-Hung Lai, Joel T Mague, Mahmoud S Tolba

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of molecular structure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shaaban K MohamedChemistry and Environmental Division, Manchester Metropolitan University, Manchester M1 5GD, United Kingdom.
Youness El BakriDepartment of Theoretical and Applied Chemistry, South Ural State University, Lenin prospect 76, Chelyabinsk 454080, Russia.
Dalia A AbdulDepartment of Chemistry, College of Science, university of Sulaimani, Sulaimania, Iraq.
Sajjad AhmadDepartment of Health and Biological Sciences, Abasyn University, Peshawar 25000, Pakistan.
Mustafa R AlbayatiKirkuk University, College of Science, Department of Chemistry, Kirkuk, Iraq.
Chin-Hung LaiDepartment of Medical Applied Chemistry, Chung Shan Medical University, Taichung 40241, Taiwan.
Joel T MagueDepartment of Chemistry, Tulane University, New Orleans, LA 70118, United States.
Mahmoud S TolbaChemistry Department, Faculty of Science, New Valley University, El-Kharja 72511, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the fall of 2019, a new type of coronavirus took place in Wuhan city, China, and rapidly spread across the world and urges the scientific community to develop antiviral therapeutic agents. In our effort we have synthesized a new hydrazide derivative, (

Indexed as

Crystal structureyDFT calculationsHydrazideMolecular dockingMolecular dynamics simulationsSARS-CoV-2

Identifiers

PMID35663190
PMCPMC9142792

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.