Evidence map›Paper›PMID 35663114›Full record

ArticleJAMIA open2022

A machine learning approach to identifying delirium from electronic health records.

Jae Hyun Kim, May Hua, Robert A Whittington, Junghwan Lee, Cong Liu, Casey N Ta, Edward R Marcantonio, Terry E Goldberg, Chunhua Weng

Abstract read
In one paragraph

Article in JAMIA open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jae Hyun KimDepartment of Biomedical Informatics, Columbia University, New York, New York, USA.
May HuaDepartment of Anesthesiology, Columbia University Medical Center, New York Presbyterian Hospital, New York, New York, USA.
Robert A WhittingtonDepartment of Anesthesiology, Columbia University Medical Center, New York Presbyterian Hospital, New York, New York, USA.
Junghwan LeeDepartment of Biomedical Informatics, Columbia University, New York, New York, USA.
Cong LiuDepartment of Biomedical Informatics, Columbia University, New York, New York, USA.ORCID https://orcid.org/0000-0001-6024-3037
Casey N TaDepartment of Biomedical Informatics, Columbia University, New York, New York, USA.
Edward R MarcantonioHarvard Medical School, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-2911-4250
Terry E GoldbergDepartment of Anesthesiology, Columbia University Medical Center, New York Presbyterian Hospital, New York, New York, USA.
Chunhua WengDepartment of Biomedical Informatics, Columbia University, New York, New York, USA.

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Bridging the Semantic Gap Between Research Eligibility Criteria and Clinical DataR01LM009886 · NLM · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WENG, CHUNHUA · 2009 to 2020
$5.3M
Translator Red Knowledge (TReK)OT2TR003434 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DUMONTIER, MICHEL, TA, CASEY NGHIA · 2020 to 2024
$2.3M
NCATS NIH HHS OT2 TR003434NCATS NIH HHS UL1 TR001873NLM NIH HHS R01 LM009886
6 · The paper itself

Abstract

The identification of delirium in electronic health records (EHRs) remains difficult due to inadequate assessment or under-documentation. The purpose of this research is to present a classification model that identifies delirium using retrospective EHR data. Delirium was confirmed with the Confusion Assessment Method for the Intensive Care Unit. Age, sex, Elixhauser comorbidity index, drug exposures, and diagnoses were used as features. The model was developed based on the Columbia University Irving Medical Center EHR data and further validated with the Medical Information Mart for Intensive Care III dataset. Seventy-six patients from Surgical/Cardiothoracic ICU were included in the model. The logistic regression model achieved the best performance in identifying delirium; mean AUC of 0.874 ± 0.033. The mean positive predictive value of the logistic regression model was 0.80. The model promises to identify delirium cases with EHR data, thereby enable a sustainable infrastructure to build a retrospective cohort of delirium.

Indexed as

Confusion Assessment Method for the Intensive Care Unit (CAM-ICU)deliriumelectronic health recordslogistic regressionmachine learning model

Identifiers

PMID35663114
PMCPMC9152701

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.