ArticleNature cardiovascular research2022
Fibroblast growth factor homologous factors serve as a molecular rheostat in tuning arrhythmogenic cardiac late sodium current.
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Article in Nature cardiovascular research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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0cells of the map it votes in
21citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
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Who cites it
21 citing papers in PubMed, 28 citations in OpenAlex.
- A bifunctional actuator to correct loss-of-function deficits in cardiac voltage-gated sodium channels.Science advances · 2026Article
- Calmodulin acts as a selective switch in FGF12A-mediated regulation of the cardiac sodium channel Nav1.5.The Journal of biological chemistry · 2026Article
- Targeting Arrhythmogenic Late Sodium Current by FHF1Circulation research · 2026Article
- Targeting Late NaCirculation research · 2026Article
- Nanoscale organization in the cell membrane dynamically modulates the biophysics of voltage-gated sodium channels.Nature communications · 2026Article
- In Vivo Expression of an SCA27A-LinkedThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Calcium interaction with Nav1.5 via FGF12A and CaM binding.bioRxiv : the preprint server for biology · 2026Article
- FGF13 is not secreted from mouse neurons.JCI insight · 2026Article
- Article
- The NaV1.5 auxiliary subunit FGF13 modulates channels by regulating membrane cholesterol independent of channel binding.The Journal of clinical investigation · 2025Article
- Effects of open-channel blocking peptides in NaBiophysical journal · 2025Article
- Loss of intracellular FGF14 (iFGF14) increases excitability of mature hippocampal pyramidal neurons.The Journal of general physiology · 2025Article
- A genetically encoded actuator boosts L-type calcium channel function in diverse physiological settings.Science advances · 2024Article
- Decreased Left Atrial Cardiomyocyte Fibroblast Growth Factor 13 Expression Increases Vulnerability to Postoperative Atrial Fibrillation in Humans.Journal of the American Heart Association · 2024Article
- Advances in understanding of cardiac sodium channel structure/function and their relation to disease pathogenesis and treatment.Heart rhythm · 2024Article
- Determinants of iFGF13-mediated regulation of myocardial voltage-gated sodium (NaV) channels in mouse.The Journal of general physiology · 2023Article
- New insights on cardiac Na channel block by an atypical anti-arrhythmic drug.Nature cardiovascular research · 2023Article
- Differential regulation of cardiac sodium channels by intracellular fibroblast growth factors.The Journal of general physiology · 2023Article
- NaV1.6 dysregulation within myocardial T-tubules by D96V calmodulin enhances proarrhythmic sodium and calcium mishandling.The Journal of clinical investigation · 2023Article
- BIOLOGICAL ANTIARRHYTHMICS-SODIUM CHANNEL INTERACTING PROTEINS.Transactions of the American Clinical and Climatological Association · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 4 institutions in 1 country.
Nourdine ChakouriDepartment of Physiology and Cellular Biophysics, Columbia University, New York, NY, USA.
Sharen RivasDepartment of Physiology and Cellular Biophysics, Columbia University, New York, NY, USA.
Daniel RoybalDepartment of Pharmacology, Columbia University, New York, NY, USA.
Lin YangDivision of Cardiology, Department of Medicine, Columbia University, New York, NY, USA.
Johanna DiazDepartment of Physiology and Cellular Biophysics, Columbia University, New York, NY, USA.
Allen HsuDepartment of Physiology and Cellular Biophysics, Columbia University, New York, NY, USA.
Ryan MahlingDepartment of Physiology and Cellular Biophysics, Columbia University, New York, NY, USA.
Bi-Xing ChenDivision of Cardiology, Department of Medicine, Columbia University, New York, NY, USA.
Josiah O OwoyemiDepartment Physiology, University of Maryland, Baltimore, MD, USA.
Deborah DiSilvestreDepartment Physiology, University of Maryland, Baltimore, MD, USA.
Dario SirabellaColumbia Stem Cell Initiative, Stem Cell Core, Columbia University Irving Medical Center, NY, USA.
Barbara CorneoColumbia Stem Cell Initiative, Stem Cell Core, Columbia University Irving Medical Center, NY, USA.
Gordon F TomaselliDepartment of Medicine, Albert Einstein College of Medicine, New York, NY, USA.
Ivy E DickDepartment Physiology, University of Maryland, Baltimore, MD, USA.
Steven O MarxDepartment of Pharmacology, Columbia University, New York, NY, USA.
Manu Ben-JohnyDepartment of Physiology and Cellular Biophysics, Columbia University, New York, NY, USA.
Columbia University · USUniversity of Maryland, Baltimore · USNew York Stem Cell Foundation · USAlbert Einstein College of Medicine · US
Funding
Tumor Biology and Microenvironment ProgramP30CA013696 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Parisa Tehranifar · 1985 to 2026
$115.3MExploring the Molecular Physiology of Atrial FibrillationR01HL140934 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MARKS, ANDREW ROBERT, MARX, STEVEN O · 2018 to 2025
$6.0MTraining in Cardiovascular Translational ResearchT32HL120826 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MARKS, ANDREW ROBERT, TABAS, IRA A · 2014 to 2023
$4.7MCalmodulin Regulation Na Channels: From Function and Structure to DiseaseR01HL128743 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI ALDRICH, RICHARD, AMZEL, L. MARIO · 2016 to 2019
$4.2MDynamic changes of the Nav1.5 interactome and contributions to heart failureR01HL160089 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI MARX, STEVEN O, PITT, GEOFFREY S · 2021 to 2024
$2.7MMultidisciplinary Research Training in Cardiovascular DiseaseT32HL160520 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Geoffrey S Pitt, Jonathan W. Weinsaft · 2022 to 2026
$2.0MTuning of CaV channel dynamics by stac proteinsR01NS110672 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI JOHNY, MANU BEN · 2019 to 2023
$1.7MBecton Dickinson LSR II Analytical Flow CytometerS10RR027050 · NCRR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CLYNES, RAPHAEL A. · 2011 to 2011
$413kNCI NIH HHS P30 CA013696NCRR NIH HHS S10 RR027050NHLBI NIH HHS R01 HL128743NHLBI NIH HHS R01 HL140934NHLBI NIH HHS R01 HL160089NHLBI NIH HHS T32 HL120826NHLBI NIH HHS T32 HL160520NINDS NIH HHS R01 NS110672
Abstract
Voltage-gated sodium (Nav1.5) channels support the genesis and brisk spatial propagation of action potentials in the heart. Disruption of Na
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.