ArticleFrontiers in pharmacology2022
Framework Development for Clinical Comprehensive Evaluation of Drugs-a Study Protocol Using the Delphi Method and Analytic Hierarchy Process.
Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Developing a readiness evaluation framework for public hospital-led digital home nursing services in China: a Delphi-AHP study.BMC nursing · 2026Article
- Informing Hospital Formulary Decisions in China: A Multi-Criteria Value Framework for GLP-1 Receptor Agonists.Risk management and healthcare policy · 2026Article
- A Clinical Comprehensive Evaluation of Long-Acting GLP-1 Receptor Agonists in Type 2 Diabetes Management.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- Developing an Evaluation Index System for Service Capability of Internet Hospitals in China: Mixed Methods Study.Journal of medical Internet research · 2025Article
- Application of a Value Framework to Determine the Value of Prophylaxis Versus On-Demand Treatment in Adults with Hemophilia A in China.Advances in therapy · 2025Article
- A Study on the Current Situation and Factors Influencing the General Practice Ability of Clinical Undergraduate Students in China.Healthcare (Basel, Switzerland) · 2025Article
- Developing a value assessment index system of anti-tumour commercial Chinese polyherbal preparation in China: a modified Delphi study.Frontiers in pharmacology · 2025Article
- Development of a psychological management intervention protocol for colorectal cancer patients: a Delphi study on benefit finding.PloS one · 2025Article
- Developing quality indicators for cancer hospitals in China: a national modified Delphi process.BMJ open · 2024Review
- Strategies to preventing pressure injuries among intensive care unit patients mechanically ventilated in prone position: a systematic review and a Delphi study.Frontiers in medicine · 2023Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Measuring the value of drugs to help make health-care decisions is a complex process which involves confronting trade-offs among multiple objectives. Although guidelines have been released for clinical comprehensive evaluation of drugs, refinement is required when considering a specific drug used in a specific disease. In this study, a two-level framework for clinical comprehensive evaluation of drugs will be developed. Six first-level indicators, including safety, efficacy, costs/cost-effectiveness, novelty, suitability, and accessibility will be evaluated according to the Chinese Guideline for Clinical Comprehensive Evaluation of Drugs. The second-level components involved in the framework will be first validated by the Delphi method and subsequently compared with one another to get the index weight based on the Analytic Hierarchy Process (AHP). The scoring criteria of each component in the framework will also be determined by the Delphi method and AHP. The scoring criteria of components representing therapeutic effects will involve both score of therapeutic effects and score of evidence quality. With the evidence of the drug to be evaluated, the score of each component will be obtained according to the established scoring criteria, and the overall comprehensive score value of the drug will be calculated, which will assist the evidence-based decision making.
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