Evidence map›Paper›PMID 35662692›Full record

ArticleFrontiers in pharmacology2022

Structural and Functional Characterization of a Novel Scorpion Toxin that Inhibits Na

Kiran George, Diego Lopez-Mateos, Tarek Mohamed Abd El-Aziz, Yucheng Xiao, Jake Kline, Hong Bao, Syed Raza, James D Stockand, Theodore R Cummins, Luca Fornelli and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Kiran GeorgeDepartment of Biology, University of Oklahoma, Norman, OK, United States.
Diego Lopez-MateosDepartment of Physiology and Membrane Biology, University of California, Davis, Davis, CA, United States.
Tarek Mohamed Abd El-AzizDepartment of Cellular and Integrative Physiology, University of Texas Health Science Center San Antonio, San Antonio, TX, United States.
Yucheng XiaoDepartment of Biology, School of Science, Indiana University-Purdue University Indianapolis, Indianapolis, IN, United States.
Jake KlineDepartment of Biology, University of Oklahoma, Norman, OK, United States.
Hong BaoDepartment of Biology, University of Oklahoma, Norman, OK, United States.
Syed RazaDepartment of Biology, University of Oklahoma, Norman, OK, United States.
James D StockandDepartment of Cellular and Integrative Physiology, University of Texas Health Science Center San Antonio, San Antonio, TX, United States.
Theodore R CumminsDepartment of Biology, School of Science, Indiana University-Purdue University Indianapolis, Indianapolis, IN, United States.
Luca FornelliDepartment of Biology, University of Oklahoma, Norman, OK, United States.
Matthew P RoweDepartment of Biology, University of Oklahoma, Norman, OK, United States.
Vladimir Yarov-YarovoyDepartment of Physiology and Membrane Biology, University of California, Davis, Davis, CA, United States.
Ashlee H RoweDepartment of Biology, University of Oklahoma, Norman, OK, United States.
University of Oklahoma · USUniversity of California, Davis · USUniversity of Indianapolis · USMinia University · EGThe University of Texas Health Science Center at San Antonio · US

Funding

Structure-Function Studies of MsvR, a Methanogen-Specific Transcriptional RegulaP20GM103640 · NIGMS · UNIVERSITY OF OKLAHOMA · PI MOOERS, BLAINE H. M. · 2012 to 2021
$20.4M
Sodium channels and electrogenesis in sensory neuronsR01NS053422 · NINDS · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI CUMMINS, THEODORE R · 2006 to 2019
$4.6M
NIGMS NIH HHS P20 GM103640NINDS NIH HHS R01 NS053422
6 · The paper itself

Abstract

Voltage-gated sodium channel Na

Indexed as

AZ bark scorpiongrasshopper miceNaTx36Nav1.8neurotoxinslow inactivationvenomvoltage-gated sodium channel

Identifiers

PMID35662692
PMCPMC9160825
OpenAlexW4280603864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.