Evidence map›Paper›PMID 35662442›Full record

ReviewEndocrinology and metabolism clinics of North America2022

2022 Update on Clinical Management of Graves Disease and Thyroid Eye Disease.

Thanh D Hoang, Derek J Stocker, Eva L Chou, Henry B Burch

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Endocrinology and metabolism clinics of North America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06392906 (Orbital Radiotherapy in Grave's Ophthalmopathy 1 Week vs 2 Weeks), which is not on this map. Cited by 72 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06392906 phase3recruitingnot on this mapstarted 2024, after this paper: background citation

Orbital Radiotherapy in Grave's Ophthalmopathy 1 Week vs 2 Weeks: A Phase II Randomized Controlled Trial (OraGO-1 Trial)

TypeinterventionalSponsorJanjira PetsuksiriRan2024 to 2028Enrolled68ConditionsThyroid Associated OphthalmopathyArmsShort course radiation therapy, Standard course radiation therapy
3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Machine Learning-Based Cytokine Endotyping of Thyroid Eye Disease.Investigative ophthalmology & visual science · 2026
    Article
  5. Review
  6. Article
  7. Treatment outcomes in patients with relapsed Graves' disease.Archives of endocrinology and metabolism · 2026
    Article
  8. Article
  9. Benefits of thermal imaging in orbital inflammation disorders.Journal of ophthalmic inflammation and infection · 2026
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Observational
  20. Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thanh D HoangDivision of Diabetes, Endocrinology and Metabolism, Walter Reed National Military Medical Center, 8901 Wisconsin Avenue, Bethesda, MD 20819, USA; Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
Derek J StockerDepartment of Radiology, Nuclear Medicine Service, Walter Reed National Military Medical Center, 8901 Wisconsin Avenue, Bethesda, MD 20819, USA; Departments of Internal Medicine, Pathology, and Radiologic Sciences Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
Eva L ChouDepartment of Ophthalmology, Oculoplastic Service, Walter Reed National Military Medical Center, 8901 Wisconsin Avenue, Bethesda, MD 20819, USA; Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
Henry B BurchDivision of Diabetes, Endocrinology and Metabolic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 6707 Democracy Boulevard, Room 6054, Bethesda, MD 20892-5460, USA; Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA. Electronic address: Henry.Burch@nih.gov.

Funding

Intramural NIH HHS Z99 DK999999
6 · The paper itself

Abstract

The management of hyperthyroidism and extrathyroidal manifestations of Graves disease remains complex. Considerations that include patient preference, age, comorbidity, pregnancy, tobacco smoking, and social determinants of health must all be weaved into a cohesive management plan. A multidisciplinary team is required to manage all aspects of Graves disease, particularly thyroid eye disease, for which new therapeutic options are now available.

Indexed as

Graves DiseaseGraves OphthalmopathyAntithyroid AgentsFemaleHumansIodine RadioisotopesPregnancyThyroidectomyAntithyroid AgentsIodine RadioisotopesAntithyroid drugsGraves diseaseHyperthyroidismRadioiodine therapyThyroidectomyThyroid eye disease

Identifiers

PMID35662442
PMCPMC9174594

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.