Evidence map›Paper›PMID 35662187›Full record

ReviewNeural regeneration research2022

The roles of microRNAs in spinal cord ischemia-reperfusion injury.

Feng-Shou Chen, Xiang-Yi Tong, Bo Fang, Dan Wang, Xiao-Qian Li, Zai-Li Zhang

Abstract readReview
In one paragraph

Review in Neural regeneration research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  10. Research progress on long non-coding RNAs for spinal cord injury.Journal of orthopaedic surgery and research · 2023
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Feng-Shou ChenDepartment of Anesthesiology, the First Hospital of China Medical University, Shenyang, Liaoning Province, China.
Xiang-Yi TongDepartment of Anesthesiology, the First Hospital of China Medical University, Shenyang, Liaoning Province, China.
Bo FangDepartment of Anesthesiology, the First Hospital of China Medical University, Shenyang, Liaoning Province, China.
Dan WangDepartment of Anesthesiology, the First Hospital of China Medical University, Shenyang, Liaoning Province, China.
Xiao-Qian LiDepartment of Anesthesiology, the First Hospital of China Medical University, Shenyang, Liaoning Province, China.
Zai-Li ZhangDepartment of Anesthesiology, the First Hospital of China Medical University, Shenyang, Liaoning Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spinal cord ischemia/reperfusion injury is a devastating medical disorder with poor prognosis that is associated with several pathophysiological conditions. However, multiple stimuli can trigger SCII, so the underlying mechanism of this pathology has not yet been fully established. MicroRNAs (miRNAs) are a class of non-coding RNAs that mediate a variety of nervous system diseases and regulate numerous physiological functions, including apoptosis, autophagy, inflammation, and blood-spinal cord barrier damage. miRNA expression profiles are known to be altered after spinal cord ischemia/reperfusion injury. Therefore, gaining a better understanding of the significant roles that miRNAs play in spinal cord ischemia/reperfusion injury could help develop potential preventive and therapeutic strategies for spinal cord ischemia/reperfusion injury. This review summarizes the current state of our knowledge about the relationship between miRNAs and spinal cord ischemia/reperfusion injury, as well as potential miRNAs that could be targeted to treat spinal cord ischemia/reperfusion injury.

Indexed as

apoptosisautophagyblood-spinal cord barrierinflammationmicroRNAspathophysiologyreviewspinal cord ischemia-reperfusion injury

Identifiers

PMID35662187
PMCPMC9165398

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.