Evidence map›Paper›PMID 35661920›Full record

ArticleCell and tissue research2022

Desmin deficiency affects the microenvironment of the cardiac side population and Sca1

Sofia Nikouli, Mary Tsikitis, Christina Raftopoulou, Sarantis Gagos, Stelios Psarras, Yassemi Capetanaki

Abstract read
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In one paragraph

Article in Cell and tissue research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sofia NikouliCenter of Basic Research, Biomedical Research Foundation, Academy of Athens, 4 Soranou Ephessiou St., Athens, 11527, Greece.
Mary TsikitisCenter of Basic Research, Biomedical Research Foundation, Academy of Athens, 4 Soranou Ephessiou St., Athens, 11527, Greece.
Christina RaftopoulouCenter of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation, Academy of Athens, 4 Soranou Ephessiou St., Athens, 11527, Greece.
Sarantis GagosCenter of Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation, Academy of Athens, 4 Soranou Ephessiou St., Athens, 11527, Greece.
Stelios PsarrasCenter of Basic Research, Biomedical Research Foundation, Academy of Athens, 4 Soranou Ephessiou St., Athens, 11527, Greece.
Yassemi CapetanakiCenter of Basic Research, Biomedical Research Foundation, Academy of Athens, 4 Soranou Ephessiou St., Athens, 11527, Greece. ycapetanaki@bioacademy.gr.ORCID http://orcid.org/0000-0002-3089-0767
Academy of Athens · GR

Funding

Hellenic Foundation for Research and Innovation ESPA 09SYN-21- 966Hellenic Foundation for Research and Innovation Excellence II/ARISTEIA II 5342
6 · The paper itself

Abstract

The heart's limited regenerative capacity raises the need for novel stem cell-based therapeutic approaches for cardiac regeneration. However, the use of stem cells is restrictive due to poor determination of their properties and the factors that regulate them. Here, we investigated the role of desmin, the major muscle-specific intermediate filament protein, in the characteristics and differentiation capacity of cardiac side population (CSP) and Sca1

Indexed as

Myocytes, CardiacStem CellsAnimalsCell DifferentiationDesminMiceRNA, MessengerTranscription FactorsDesminRNA, MessengerTranscription FactorsCardiac stem cellsCardiomyocyte differentiationDesminIntermediate filamentsStem cell microenvironment

Identifiers

PMID35661920
OpenAlexW4281678613

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.