ArticlePediatric research2023
Incidence of primary congenital hypothyroidism over 24 years in Finland.
Article in Pediatric research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- A Comparative Assessment of Large Language Models in Congenital Hypothyroidism: Reliability, Quality and ReadabilityJournal of clinical research in pediatric endocrinology · 2026Article
- Trajectories of growth and language development among children with congenital hypothyroidism concerning gender differences: Egyptian study.BMC pediatrics · 2026Article
- Universal Decentralized Cord Blood TSH Screening Should Be Offered as Routine Delivery Care in Limited-Resource Settings.International journal of neonatal screening · 2025Article
- Timing of adiposity rebound in children with congenital hypothyroidism diagnosed by newborn screening and treated with Levothyroxine.Italian journal of pediatrics · 2025Observational
- Incidence of Congenital Hypothyroidism Is Increasing in Chile.International journal of neonatal screening · 2025Article
- Newborn screening for congenital hypothyroidism: worldwide coverage 50 years after its start.European thyroid journal · 2025Review
- rs9789446 genotype as susceptibility biomarkers for congenital hypothyroidism based on population and family validation.Frontiers in genetics · 2025Article
- Identification of southern Taiwan genetic variants in thyroid dyshormonogenesis through whole-exome sequencing.The Kaohsiung journal of medical sciences · 2024Article
- Impact of Lowering TSH Cut-Off on Neonatal Screening for Congenital Hypothyroidism in Minas Gerais, Brazil.International journal of neonatal screening · 2024Article
- Current Status of Newborn Bloodspot Screening Worldwide 2024: A Comprehensive Review of Recent Activities (2020-2023).International journal of neonatal screening · 2024Review
- History of Neonatal Screening of Congenital Hypothyroidism in Portugal.International journal of neonatal screening · 2024Article
- Comorbidity in Congenital Hypothyroidism-A Nationwide, Population-based Cohort Study.The Journal of clinical endocrinology and metabolism · 2023Article
- Neonatal screening for congenital hypothyroidism: 28-year experience in the state of Minas Gerais, Brazil.Jornal de pediatriaArticle
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA rise in the incidence of congenital hypothyroidism (CH) has been reported worldwide. This nationwide study aimed to describe the secular trends and current incidence of CH in Finland.
methodsTwo independent study cohorts, a national and a regional, were collected from national registers and patient records. The national cohort represents all CH cases born in Finland between 1994 and 2017. Birth data, results of the screening test, and the incidence of CH were reviewed.
resultsBetween 1994 and 2017, 1,400,028 children were born in Finland. Of these children, 503 were diagnosed with primary CH (incidence 1:2783). Male-to-female sex ratio was 1:2.0. The nationwide incidence was 33 cases per 100,000 live births between 1994 and 1999, 38 cases per 100,000 live births between 2000 and 2005, 40 cases per 100,000 live births between 2006 and 2011, and 33 cases per 100,000 live births between 2012 and 2017. In the regional cohort (n = 139), the incidence of transient CH was 3.6%. The incidence of mild, moderate, and severe CH remained constant.
conclusionsIn Finland, the incidence of CH has not changed during the 24-year study period. IMPACT: As opposed to recent reports worldwide, the incidence of congenital hypothyroidism has not changed between 1994 and 2017 in Finland. The proportions of mild, moderate, and severe congenital hypothyroidism did not change significantly over the study period. Lowering the TSH cut-off limit or increasing immigration did not affect the incidence rate of primary congenital hypothyroidism in Finland.
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