Evidence map›Paper›PMID 35661735›Full record

ArticleEnvironmental research2022

The association between oil spill cleanup-related total hydrocarbon exposure and diabetes.

H V Jardel, L S Engel, K G Lawrence, P A Stewart, M R Stenzel, M D Curry, R K Kwok, D P Sandler

Open access · greenAbstract read
In one paragraph

Article in Environmental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

H V JardelDepartment of Epidemiology, UNC Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA. Electronic address: jahan1@ad.unc.edu.
L S EngelDepartment of Epidemiology, UNC Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA; Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, NC, USA.
K G LawrenceEpidemiology Branch, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, NC, USA.
P A StewartStewart Exposure Assessments, LLC North Arlington, Virginia, USA.
M R StenzelExposure Assessment Applications LLC Arlington, Virginia, USA.
M D CurrySocial and Scientific Systems, Inc., a DLH Holding Company Durham, NC, USA.
R K KwokEpidemiology Branch, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, NC, USA; Office of the Director, National Institute of Environmental Health Sciences, NIH, DHHS, Bethesda, MD, USA.
D P SandlerEpidemiology Branch, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, NC, USA.
National Institute of Environmental Health Sciences · USUniversity of North Carolina at Chapel Hill · USOffice of the Director · USSocial and Scientific Systems (United States) · US

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel · 2001 to 2026
$36.3M
Occupational Safety and Health and Education Research CenterT42OH008673 · OH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NYLANDER-FRENCH, LEENA A · 2005 to 2025
$27.3M
Gulf Longitudinal Follow-up (GuLF) Worker StudyZIAES102945 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI SANDLER, DALE P · 2010 to 2025
$15.3M
Exposure to volatile organic compounds and glycemic dysregulation among oil spill cleanup workersF31ES033509 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JARDEL, HANNA · 2021 to 2023
$73k
Intramural NIH HHS ZIA ES102945NIEHS NIH HHS F31 ES033509NIEHS NIH HHS P30 ES010126NIOSH CDC HHS T42 OH008673
6 · The paper itself

Abstract

backgroundAlthough evidence suggests relationships between some crude oil components and glycemic dysregulation, no studies have examined oil spill-related chemical exposures in relation to type 2 diabetes mellitus (DM) risk. This study examined the relationship between total hydrocarbon (THC) exposure among workers involved in the 2010 Deepwater Horizon (DWH) oil spill and risk of DM up to 6 years afterward.

methodsParticipants comprised 2660 oil-spill cleanup or response workers in the prospective GuLF Study who completed a clinical exam and had no self-reported DM diagnosis prior to the spill. Maximum THC exposure was estimated with a job-exposure matrix based on interview data and personal measurements taken during cleanup operations. We defined incident DM by self-reported physician diagnosis of DM, antidiabetic medication use, or a measured hemoglobin A1c value ≥ 6.5%. We used log binomial regression to estimate risk ratios (RRs) for DM across ordinal categories of THC exposure. The fully adjusted model controlled for age, sex, race/ethnicity, education, employment status, and health insurance status. We also stratified on clinical body mass index categories.

resultsWe observed an exposure-response relationship between maximum daily ordinal THC exposure level and incident DM, especially among overweight participants. RRs among overweight participants were 0.99 (95% CI: 0.37, 2.69), 1.46 (95% CI: 0.54, 3.92), and 2.11 (95% CI: 0.78, 5.74) for exposure categories 0.30-0.99 ppm, 1.00-2.99 ppm, and ≥3.00 ppm, respectively (p

conclusionWe observed suggestively increasing DM risk with increasing THC exposure level among overweight participants, but not among normal weight or obese participants.

Indexed as

Diabetes Mellitus, Type 2Occupational ExposurePetroleum PollutionWater Pollutants, ChemicalGulf of AmericaHumansHydrocarbonsOverweightProspective StudiesHydrocarbonsWater Pollutants, ChemicalDiabetesGuLF studyPetroleum hydrocarbons

Identifiers

PMID35661735
PMCPMC9267393
OpenAlexW4281658161

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.