Evidence map›Paper›PMID 35661436›Full record

ArticleCancer medicine2023

Comprehensive global collaboration in the care of 1182 pediatric oncology patients over 12 years: The Iraqi-Italian experience.

Mazin Faisal Al-Jadiry, Stefania Uccini, Anna Maria Testi, Maria Luisa Moleti, Adil Rabeea Alsaadawi, Amir Fadhil Al-Darraji, Raghad Majid Al-Saeed, Safaa A Faraj Al-Badri, Ahmed Hatem Sabhan, Hasanein Habeeb Ghali and 13 more

Abstract read
In one paragraph

Article in Cancer medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Mazin Faisal Al-JadiryDepartment of Pediatrics, College of Medicine, University of Baghdad, Oncology Unit-Children Welfare Teaching Hospital-Medical City, Baghdad, Iraq.ORCID 0000-0003-3773-9135
Stefania UcciniClinical and Molecular Medicine, Sapienza University, Rome, Italy.
Anna Maria TestiHematology, Department of Translational and Precision Medicine, Sapienza University, Rome, Italy.
Maria Luisa MoletiHematology, Department of Translational and Precision Medicine, Sapienza University, Rome, Italy.
Adil Rabeea AlsaadawiCentral Teaching Laboratory, Medical City, Pathology, Baghdad, Iraq.
Amir Fadhil Al-DarrajiOncology Unit, Children Welfare Teaching Hospital-Medical City, Baghdad, Iraq.
Raghad Majid Al-SaeedOncology Unit, Children Welfare Teaching Hospital-Medical City, Baghdad, Iraq.
Safaa A Faraj Al-BadriCollege of Medicine- Wasit University, Children's Welfare Teaching Hospital-Pediatric Oncology Unit, Medical City, Baghdad, Iraq.
Ahmed Hatem SabhanOncology Unit, Children Welfare Teaching Hospital-Medical City, Baghdad, Iraq.
Hasanein Habeeb GhaliDepartment of Pediatrics, College of Medicine, University of Baghdad, Oncology Unit-Children Welfare Teaching Hospital-Medical City, Baghdad, Iraq.
Samaher Abdulrazzaq FadhilOncology Unit, Children Welfare Teaching Hospital-Medical City, Baghdad, Iraq.
Wisam Majeed AbedHematology Laboratory Department, Children Welfare Teaching Hospital-Medical City, Baghdad, Iraq.
Najiha Ahmed AmeenHematology Laboratory Department, Children Welfare Teaching Hospital-Medical City, Baghdad, Iraq.
Yasir Saadoon AbedOncology Unit, Children Welfare Teaching Hospital-Medical City, Baghdad, Iraq.
Fawaz Salim YousifOncology Unit, Children Welfare Teaching Hospital-Medical City, Baghdad, Iraq.
Aseel Rashid AbedOncology Unit, Children Welfare Teaching Hospital-Medical City, Baghdad, Iraq.
Hanadi Munaf HusseinOncology Unit, Children Welfare Teaching Hospital-Medical City, Baghdad, Iraq.
Ahmed Mudhafar ShkaraDepartment of Pharmaceutics-College of Pharmacy, University of Baghdad, Baghdad, Iraq.
Alfonso PiciocchiGIMEMA Data Center, GIMEMA Foundation, Rome, Italy.
Sara MohamedHematology, Department of Translational and Precision Medicine, Sapienza University, Rome, Italy.
Luigi RucoClinical and Molecular Medicine, Sapienza University, Rome, Italy.
Ibrahim QaddoumiDepartment of Global Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Salma Abbas Al-HadadDepartment of Pediatrics, College of Medicine, University of Baghdad, Oncology Unit-Children Welfare Teaching Hospital-Medical City, Baghdad, Iraq.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIraq's health care system has gradually declined after several decades of wars, terrorism, and UN economic sanctions. The Oncology Unit at Children's Welfare Teaching Hospital (CWTH) in Baghdad was lacking basic facilities and support. To address this shortcoming, a humanitarian and educational partnership was established between CWTH and Sapienza University of Rome (SUR).

methodsWe investigated the outcomes of 80 online and 16 onsite educational sessions and 142 teleconsultation sessions from 2006 to 2014. We also determined the outcomes of pathology reviews by SUR of 1216 tissue specimens submitted by CWTH from 2007 until 2019 for second opinions. The primary outcomes were discordance, concordance, and changes among clinical diagnoses and pathology review findings. The measures included the frequency of teleconsultation and tele-education sessions, the topics discussed in these sessions, and the number of pathology samples requiring second opinions.

findingsA total of 500 cases were discussed via teleconsultations during the study period. The median patient age was 7 years (range, 24 days to 16·4 years), and the cases comprised 79 benign tumors, 299 leukemias, 120 lymphomas, and 97 solid tumors. The teleconsultation sessions yielded 27 diagnostic changes, 123 confirmed diagnoses, and 13 equivocal impacts. The pathology reviews by SUR were concordant for 996 (81·9%) cases, discordant for 186 (15·3%), and inconclusive for 34 (2·8%). The major cause of discordance was inadequate immunohistochemical staining. The percentage of discordance markedly decreased over time (from 40% to 10%). The cause of the improvement is multifactorial: training of two CWTH pathologists at SUR, better immunohistochemical staining, and the ongoing clinical and pathologic telemedicine activities. The partnership yielded 12 publications, six posters, and three oral presentations by CWTH investigators.

interpretationThe exchange of knowledge and expertise across continental boundaries meaningfully improved the diagnoses and management of pediatric cancer at CWTH.

Indexed as

NeoplasmsTelemedicineChildDelivery of Health CareHumansInfant, NewbornIraqMedical Oncologycancerchildrendeveloping countriespathology reviewpediatric oncologypediatric pathologyteleconsultationtelemedicine

Identifiers

PMID35661436
PMCPMC9844594

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.