Evidence map›Paper›PMID 35661347›Full record

ArticleEuropean journal of neurology2022

Neurovascular disease in Switzerland: 10-year trends show non-traditional risk factors on the rise and higher exposure in women.

Martin Hänsel, Klaus Steigmiller, Andreas R Luft, Catherine Gebhard, Ulrike Held, Susanne Wegener

Registry-linked trialAbstract read
In one paragraph

Article in European journal of neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06443268 (Cerebrovascular Disease), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06443268 recruitingnot on this mapstarted 2023, after this paper: background citation

Cerebrovascular Disease: Quality of Life (CODE: QoL)

TypeobservationalSponsorUniversity of ZurichRan2023 to 2028Enrolled680ConditionsQuality of Life, Stroke, Acute, Sexual Behavior, StressArmsquestionnaire, hair samples, blood samples, clinical exam
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Martin HänselDepartment of Neurology and Clinical Neuroscience Center, University Hospital Zurich and University of Zurich, Zurich, Switzerland.ORCID 0000-0001-9300-1130
Klaus SteigmillerDepartment of Biostatistics at Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.
Andreas R LuftDepartment of Neurology and Clinical Neuroscience Center, University Hospital Zurich and University of Zurich, Zurich, Switzerland.
Catherine GebhardDepartment of Nuclear Medicine, University Hospital Zurich and University of Zurich, Zurich, Switzerland.
Ulrike HeldDepartment of Biostatistics at Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.
Susanne WegenerDepartment of Neurology and Clinical Neuroscience Center, University Hospital Zurich and University of Zurich, Zurich, Switzerland.ORCID 0000-0003-4369-7023

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeEffective risk factor modification is the prerequisite to prevent neurovascular disease such as stroke or vascular dementia. Non-traditional vascular risk factors (nt-vrfs) including stress significantly add to the risk of neurovascular disease arising from traditional vascular risk factors (t-vrfs). In order to discover sex-specific changes that may underlie previously reported inclines in the prevalence of neurovascular and cardiovascular disease in women, 10-year trends in the prevalence of vrfs in Switzerland were assessed.

methodsAnonymized data from 22,134 participants (51% women) of the governmental Swiss Health Survey, performed every 5 years (2007, 2012 and 2017), were obtained. Epidemiological parameters, t-vrfs and nt-vrfs were analyzed in a cross-sectional study design.

resultsOver the observation period, the number of women having full-time jobs increased considerably (2007 38%, 2012 39%, 2017 44%). This was accompanied by a substantial rise in the prevalence of nt-vrfs in women and men including stress at work (2007, not available; 2012 women/men 58%/60%; 2017 women/men 66%/65%), low locus of control (women/men: 2007 21%/19%, 2012 22%/19%, 2017 25%/22%) and sleep disorders (women/men: 2007 30%/22%, 2012 28%/20%, 2017 32%/26%). Amongst t-vrfs, only the prevalence of obesity and hypercholesterolemia increased over time in both sexes, whilst other t-vrfs remained stable (hypertension [27%], diabetes [5%]) or decreased (smoking [9.4 cigarettes/day]).

conclusionsA rise in women's economic participation alongside a higher affection with nt-vrfs in the female Swiss population emphasizes the need to improve vascular risk stratification and implement effective preventive measures for neurovascular and cardiovascular disease.

Indexed as

Cardiovascular DiseasesHypertensionCross-Sectional StudiesFemaleHumansMalePrevalenceRisk FactorsSwitzerlandcardiovascular diseasecardiovascular risk factorsprevalencesexstrokeSwitzerland

Identifiers

PMID35661347
PMCPMC9541902

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.