Evidence map›Paper›PMID 35661286›Full record

ArticleCellular and molecular neurobiology2023

Lanthanum Chloride Induces Axon Abnormality Through LKB1-MARK2 and LKB1-STK25-GM130 Signaling Pathways.

Zeli Song, Haoyue Mao, Jinxuan Liu, Wenchang Sun, Shengwen Wu, Xiaobo Lu, Cuihong Jin, Jinghua Yang

Erratum issuedOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cellular and molecular neurobiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Adverse effects and underlying mechanism of rare earth elements.Environmental health : a global access science source · 2025
    Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Zeli SongDepartment of Toxicology, School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang, 110122, People's Republic of China.
Haoyue MaoDepartment of Toxicology, School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang, 110122, People's Republic of China.
Jinxuan LiuDepartment of Toxicology, School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang, 110122, People's Republic of China.
Wenchang SunDepartment of Toxicology, School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang, 110122, People's Republic of China.
Shengwen WuDepartment of Toxicology, School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang, 110122, People's Republic of China.
Xiaobo LuDepartment of Toxicology, School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang, 110122, People's Republic of China.
Cuihong JinDepartment of Toxicology, School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang, 110122, People's Republic of China.
Jinghua YangDepartment of Toxicology, School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang, 110122, People's Republic of China. jhyang@cmu.edu.cn.
China Medical University · CN

Funding

The National Natural Science Foundation of China 81773469
6 · The paper itself

Abstract

Lanthanum (La) is a natural rare-earth element that can damage the central nervous system and impair learning and memory. However, its neurotoxic mechanism remains unclear. In this study, adult female rats were divided into 4 groups and given distilled water solution containing 0%, 0.125%, 0.25%, and 0.5% LaCl

Indexed as

AxonsLanthanumAnimalsFemaleProtein Serine-Threonine KinasesRatsRats, WistarSignal TransductionLanthanumlanthanum chlorideMARK2 protein, ratProtein Serine-Threonine KinasesAxonLanthanumLearning and memoryLKB1

Identifiers

PMID35661286
PMCPMC11414431
OpenAlexW4281909819

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.