Evidence map›Paper›PMID 35660784›Full record

ArticleEBioMedicine2022

Poor ovarian response is associated with air pollutants: A multicentre study in China.

Shanshan Wu, Guimin Hao, Yunshan Zhang, Xiujuan Chen, Haiqin Ren, Yanli Fan, Yinfeng Zhang, Xingyu Bi, Chen Du, Lina Bai and 2 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in EBioMedicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Shanshan WuCentre of Reproductive Medicine, Department of Obstetrics and Gynaecology, Shengjing Hospital of China Medical University, No. 39 Huaxiang Road, Tiexi District, Shenyang, Liaoning 110022, PR China; Key Laboratory of Reproductive Dysfunction Disease and Fertility Remodelling of Liaoning Province, Shenyang, Liaoning 110022, PR China.
Guimin HaoDepartment of Reproductive Medicine, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei 050000, PR China.
Yunshan ZhangTianjin Central Hospital of Obstetrics and Gynaecology, Tianjin 300100, PR China.
Xiujuan ChenReproductive Medicine Centre, Affiliated Hospital, Inner Mongolia Medical University, Hohhot, Inner Mongolia, 010050, PR China.
Haiqin RenJinghua Hospital, Shenyang, Liaoning 110022, PR China.
Yanli FanDepartment of Reproductive Medicine, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei 050000, PR China.
Yinfeng ZhangTianjin Central Hospital of Obstetrics and Gynaecology, Tianjin 300100, PR China.
Xingyu BiCentre of Reproductive Medicine, Children's Hospital of Shanxi and Women Health Centre of Shanxi, Taiyuan, Shanxi 030013, PR China.
Chen DuReproductive Medicine Centre, Affiliated Hospital, Inner Mongolia Medical University, Hohhot, Inner Mongolia, 010050, PR China.
Lina BaiJinghua Hospital, Shenyang, Liaoning 110022, PR China.
Xueqing WuCentre of Reproductive Medicine, Children's Hospital of Shanxi and Women Health Centre of Shanxi, Taiyuan, Shanxi 030013, PR China. Electronic address: wuxueqq@hotmail.com.
Jichun TanCentre of Reproductive Medicine, Department of Obstetrics and Gynaecology, Shengjing Hospital of China Medical University, No. 39 Huaxiang Road, Tiexi District, Shenyang, Liaoning 110022, PR China; Key Laboratory of Reproductive Dysfunction Disease and Fertility Remodelling of Liaoning Province, Shenyang, Liaoning 110022, PR China. Electronic address: tjczjh@163.com.
Hebei Medical University · CNInner Mongolia Medical University · CNShenyang Center for Disease Control and Prevention · CNTianjin Central Hospital of Gynecology Obstetrics · CNShanxi Provincial Children's Hospital · CNShaoxing City Women and Children Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHuman evidence on the association between air pollution and ovarian response is scarce. Poor ovarian response (POR) with an incidence of 5-35% is a tricky problem in IVF treatment.

methodsIn this large-scale multicentre study, we included 2186 women with POR (< 4 oocytes retrieved) and 7033 women with a normal ovarian response (10-15 oocytes retrieved), who underwent their first in vitro fertilization treatment in five cities in northern China during 2015-2020. Average concentrations of six air pollutants (PM

findingsWe detected that increased SO

interpretationThe findings provide human evidence for adverse effects of exposure to ambient air pollutants on ovarian response and underscore the need to reduce ambient air pollution exposure in women of reproductive age to protect human fertility.

fundingThis study was granted from the National Key Research and Development Program (2018YFC1004203), the Major Special Construction Plan for Discipline Construction Project of China Medical University (3110118033), the Shengjing Freelance Researcher Plan of Shengjing Hospital of China Medical University, and the National Natural Science Foundation of China (82071601), the Central Government Special Fund for Local Science and Technology Development (2020JH6/10500006).

Indexed as

Air PollutantsAir PollutionAdultChinaFemaleFertilization in VitroHumansIncidenceParticulate MatterAir PollutantsParticulate MatterAir pollutionIn vitro fertilizationMulticentreOvarian reservePoor ovarian response

Identifiers

PMID35660784
PMCPMC9163489
OpenAlexW4281651330

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.