Evidence map›Paper›PMID 35660734›Full record

ArticleNature communications2022

Ex vivo-expanded human CD19

S Shankar, J Stolp, S C Juvet, J Beckett, P S Macklin, F Issa, J Hester, K J Wood

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. B cells in cancer: functions, mechanisms and therapeutic advances.Signal transduction and targeted therapy · 2026
    Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Gene editing of CD3 epsilon to redirect regulatory T cells for adoptive T cell transfer.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  13. Expansion of B10 cellsInternational journal of molecular medicine · 2025
    Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Ex vivo-generated human CD1cMolecular therapy : the journal of the American Society of Gene Therapy · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

S ShankarTranslational Research and Immunology Group, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK. sushma.shankar@nds.ox.ac.uk.ORCID 0000-0002-9843-6245
J StolpTranslational Research and Immunology Group, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.
S C JuvetTranslational Research and Immunology Group, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.ORCID 0000-0002-7243-556X
J BeckettTranslational Research and Immunology Group, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.
P S MacklinNuffield Department of Medicine Research Building, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
F IssaTranslational Research and Immunology Group, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.ORCID 0000-0002-8279-7732
J HesterTranslational Research and Immunology Group, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK.ORCID 0000-0002-7466-3849
K J WoodTranslational Research and Immunology Group, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK. kathryn.wood@nds.ox.ac.uk.
University of Oxford · GBNuffield Orthopaedic Centre · GB

Funding

Department of Health RCF20/055Wellcome TrustWellcome Trust 097932/Z/11/ZWellcome Trust 211122/Z/18/ZWellcome Trust HJRWQJ00Wellcome Trust ISSF0007267
6 · The paper itself

Abstract

Regulatory B cells (Breg) are a heterogenous population with immune-modulating functions. The rarity of human IL-10

Indexed as

B-Lymphocytes, RegulatoryCarcinoma, Squamous CellSkin NeoplasmsAnimalsAntigens, CD19HumansInterleukin-10Lymphocyte ActivationMiceSTAT3 Transcription FactorAntigens, CD19Interleukin-10STAT3 protein, humanSTAT3 Transcription Factor

Identifiers

PMID35660734
PMCPMC9166804
OpenAlexW4281726392

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.