Evidence map›Paper›PMID 35660476›Full record

ArticleAmerican heart journal2022

Differences in incident and recurrent myocardial infarction among White and Black individuals aged 35 to 84: Findings from the ARIC community surveillance study.

Duygu Islek, Alvaro Alonso, Wayne Rosamond, Anna Kucharska-Newton, Yejin Mok, Kunihiro Matsushita, Silvia Koton, Michael Joseph Blaha, Mohammed K Ali, Amita Manatunga and 1 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in American heart journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07032389 (Polypill Strategy for the Treatment of Patients After Acute Coronary Syndromes - A Multicenter Randomized Controlled Trial), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07032389 phase2recruitingnot on this mapstarted 2025, after this paper: background citation

Polypill Strategy for the Treatment of Patients After Acute Coronary Syndromes - A Multicenter Randomized Controlled Trial

TypeinterventionalSponsorUniversity of Texas Southwestern Medical CenterRan2025 to 2030Enrolled1,000ConditionsAcute Coronary SyndromeArmsPolypill
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Duygu IslekDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA; Department of Epidemiology, Laney Graduate School, Emory University, Atlanta, GA. Electronic address: dislek@emory.edu.
Alvaro AlonsoDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA.
Wayne RosamondDepartment of Epidemiology, University of North Carolina at Chapel Hill, Gillings School of Global Public Health, Chapel Hill, NC.
Anna Kucharska-NewtonDepartment of Epidemiology, University of North Carolina at Chapel Hill, Gillings School of Global Public Health, Chapel Hill, NC.
Yejin MokDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Kunihiro MatsushitaDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Silvia KotonDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD; Department of Nursing, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Michael Joseph BlahaDivision of Cardiology, School of Medicine, Johns Hopkins University, Baltimore, MD.
Mohammed K AliDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA; Emory Global Diabetes Research Center, Hubert Department of Global Health, Emory University, Atlanta, GA; Department of Family and Preventive Medicine, School of Medicine, Emory University, Atlanta, GA.
Amita ManatungaDepartment of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GA.
Viola VaccarinoDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA; Division of Cardiology, School of Medicine, Emory University, Atlanta, GA.
Emory University · USJohns Hopkins University · USUniversity of North Carolina at Chapel Hill · US

Funding

Translational Research Core - Engagement and Behavior ChangeP30DK111024 · NIDDK · EMORY UNIVERSITY · PI Mohammed Kumail Ali · 2016 to 2026
$13.4M
Mentoring in patient-oriented atrial fibrillation and cardiovascular researchK24HL148521 · NHLBI · EMORY UNIVERSITY · PI ALONSO, ALVARO · 2019 to 2023
$593k
NHLBI NIH HHS K24 HL148521NIDDK NIH HHS P30 DK111024
6 · The paper itself

Abstract

backgroundNo previous study has examined racial differences in recurrent acute myocardial infarction (AMI) in a community population. We aimed to examine racial differences in recurrent AMI risk, along with first AMI risk in a community population.

methodsThe community surveillance of the Atherosclerosis Risk in Communities Study (2005-2014) included 470,000 people 35 to 84 years old in 4 U.S. communities. Hospitalizations for recurrent and first AMI were identified from ICD-9-CM discharge codes. Poisson regression models were used to compare recurrent and first AMI risk ratios between Black and White residents.

resultsRecurrent and first AMI risk per 1,000 persons were 8.8 (95% CI, 8.3-9.2) and 20.7 (95% CI, 20.0-21.4) in Black men, 6.8 (95% CI, 6.5-7.0) and 14.1 (95% CI, 13.8-14.5) in White men, 5.3 (95% CI, 5.0-5.7) and 16.2 (95% CI, 15.6-16.8) in Black women, and 3.1 (95% CI, 3.0-3.3) and 8.8 (95% CI, 8.6-9.0) in White women, respectively. The age-adjusted risk ratios (RR) of recurrent AMI were higher in Black men vs White men (RR, 1.58 95% CI, 1.30-1.92) and Black women vs White women (RR, 2.09 95% CI, 1.64-2.66). The corresponding RRs were slightly lower for first AMI: Black men vs White men, RR, 1.49 (95% CI, 1.30-1.71) and Black women vs White women, RR, 1.65 (95% CI, 1.42-1.92)

conclusionsLarge disparities exist by race for recurrent AMI risk in the community. The magnitude of disparities is stronger for recurrent events than for first events, and particularly among women.

Indexed as

AtherosclerosisMyocardial InfarctionAdultAgedAged, 80 and overBlack PeopleFemaleHospitalizationHumansMaleMiddle AgedSex FactorsCommunity surveillanceMyocardial infarction outcomesRacial differencesRacial disparitiesRecurrent myocardial infarctionRisk

Identifiers

PMID35660476
PMCPMC10007857
OpenAlexW4281715075

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.