Evidence map›Paper›PMID 35660134›Full record

ArticleeLife2022

A general decoding strategy explains the relationship between behavior and correlated variability.

Amy M Ni, Chengcheng Huang, Brent Doiron, Marlene R Cohen

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05004649 (The Effects of Stimulus Variability in Natural Visual Scenes), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05004649 nacompletednot on this map

The Effects of Stimulus Variability in Natural Visual Scenes

TypeinterventionalSponsorUniversity of PennsylvaniaRan2021 to 2022Enrolled19ConditionsVisual PerceptionArmsPsychophysical task
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  7. Nonresponsive Neurons Improve Population Coding of Object Location.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  8. Neuron synchronization analyzed through spatial-temporal attention.Frontiers in computational neuroscience · 2025
    Article
  9. Article
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  11. Article
  12. The impact of functional correlations on task information coding.Network neuroscience (Cambridge, Mass.) · 2024
    Article
  13. Article
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Amy M NiDepartment of Neuroscience,University of Pittsburgh, Pittsburgh, United States.ORCID 0000-0002-1746-9206
Chengcheng HuangDepartment of Neuroscience,University of Pittsburgh, Pittsburgh, United States.
Brent DoironCenter for the Neural Basis of Cognition, Pittsburgh, United States.
Marlene R CohenDepartment of Neuroscience,University of Pittsburgh, Pittsburgh, United States.ORCID 0000-0001-8583-4300
University of Pittsburgh · US

Funding

Virus Production and Manipulation of Protein/Gene Expression ModuleP30EY008098 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Marlene Behrmann · 1989 to 2026
$17.8M
Validating Theoretical Models with Neurophysiology and OptogeneticsU19NS107613 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MILLER, KENNETH D, SCANZIANI, MASSIMO · 2018 to 2022
$16.7M
Using Neuronal Populations to Probe Perceptual DecisionsR01EY022930 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI COHEN, MARLENE ROCHELLE · 2013 to 2022
$3.8M
Neuronal population dynamics within and across cortical areasR01EB026953 · NIBIB · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DOIRON, BRENT D., SMITH, MATTHEW A · 2018 to 2020
$1.0M
Using Attention to Understand Cortical Population CodesR00EY020844 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI COHEN, MARLENE ROCHELLE · 2011 to 2013
$730k
Using multiple species, stimuli, and tasks to study the neural basis of visually guided behaviorK99NS118117 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI NI, AMY MEESUN · 2020 to 2021
$239k
NEI NIH HHS P30 EY008098NEI NIH HHS R00 EY020844NEI NIH HHS R01 EY022930NIBIB NIH HHS R01 EB026953NINDS NIH HHS K99 NS118117NINDS NIH HHS U19 NS107613
6 · The paper itself

Abstract

Improvements in perception are frequently accompanied by decreases in correlated variability in sensory cortex. This relationship is puzzling because overall changes in correlated variability should minimally affect optimal information coding. We hypothesize that this relationship arises because instead of using optimal strategies for decoding the specific stimuli at hand, observers prioritize

Indexed as

Visual CortexAnimalsMacaca mulattaNeuronsPhotic StimulationVisual Perceptionneural codingneurosciencenoise correlationsperceptionrhesus macaquevisual attention

Identifiers

PMID35660134
PMCPMC9170243
OpenAlexW4281666388

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.