Evidence map›Paper›PMID 35660014›Full record

ArticleClinica chimica acta; international journal of clinical chemistry2022

At-admission HbA

Andrea Valle, Javier Rodriguez, Félix Camiña, Miguel A Martínez-Olmos, Juan B Ortola, Santiago Rodriguez-Segade

Abstract read
In one paragraph

Article in Clinica chimica acta; international journal of clinical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Mean Blood Glucose Level During ICU Hospitalization is a Strong Predictor of the Mortality of COVID-19.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andrea ValleClinical Biochemistry Laboratory of University Hospital Complex, Santiago de Compostela. Travesía de la Choupana s/n. 15706-Santiago de Compostela (Spain).
Javier RodriguezClinical Biochemistry Laboratory of University Hospital Complex, Santiago de Compostela. Travesía de la Choupana s/n. 15706-Santiago de Compostela (Spain); Department of Biochemistry and Molecular Biology, University of Santiago de Compostela, Campus Vida. 15782-Santiago de Compostela (Spain).
Félix CamiñaDepartment of Biochemistry and Molecular Biology, University of Santiago de Compostela, Campus Vida. 15782-Santiago de Compostela (Spain).
Miguel A Martínez-OlmosEndocrinology and Nutrition Service of University Hospital Complex, Santiago de Compostela. Travesía de la Choupana s/n. 15706-Santiago de Compostela (Spain).
Juan B OrtolaClinical Biochemistry Laboratory of University Hospital Complex, Santiago de Compostela. Travesía de la Choupana s/n. 15706-Santiago de Compostela (Spain).
Santiago Rodriguez-SegadeClinical Biochemistry Laboratory of University Hospital Complex, Santiago de Compostela. Travesía de la Choupana s/n. 15706-Santiago de Compostela (Spain); Department of Biochemistry and Molecular Biology, University of Santiago de Compostela, Campus Vida. 15782-Santiago de Compostela (Spain). Electronic address: santiago.rodriguez-segade@usc.es.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo examine glycaemic status, and the impact of at-admission HbA1c levels on outcome, in a large group of participants hospitalized for COVID-19.

methodsWe inclued 515 participants with confirmed COVID-19 infection, with or without known diabetes, who met the following additional criteria: 1) age > 18 years, 2) HbA

resultsMean age was 70 years, 98.8% were of white race, 49% were female, 31% had known diabetes (KD), an additional 7% met the HbA1c criterion for diabetes, and 13.6% died. In participants with KD, FPG and HbA1c levels were not associated with mortality in adjusted analyses; however, in participants without KD, whereas FPG showed direct association with mortality, HbA1c showed slight inverse association.

conclusionsThere was a very high prevalence of people without KD with HbA1c levels above normal at-admission. This alteration does not seem to have been related to blood glucose levels.

Indexed as

COVID-19Diabetes Mellitus, Type 2AdultAftercareAgedBlood GlucoseFastingFemaleGlycated HemoglobinHumansMaleMiddle AgedPatient DischargeBlood GlucoseGlycated HemoglobinClinical Outcome, COVID-19HbA(1c)MortalityRisk factor

Identifiers

PMID35660014
PMCPMC9161671

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.