ArticleSexual medicine2022
Quality of Life, Self-Esteem, and Depression Among Thai Transgender Women Before and After Male-to-Female Gender Confirmation Surgery: A Prospective Cohort Observational Study.
Article in Sexual medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Do hormones and surgery improve the health of adults with gender incongruence? A systematic review of patient reported outcomes.ANZ journal of surgery · 2025Pooled it
- Implementation of Patient-Reported Outcome Measures for Gender-Affirming Care Worldwide: A Systematic Review.JAMA network open · 2023Pooled it
- Impact of Gender-Affirming Surgery on Psychiatric Outcomes and Quality of Life in Transgender Individuals: A Systematic Review of Longitudinal Cohort Studies.Journal of clinical medicine · 2026Review
- Depression and Suicidal Ideation Among Men who have sex with men and Transgender Women in Chiang Mai, Thailand.F1000Research · 2026Article
- Lived experiences, health-seeking behaviour, quality of life, and self-esteem among transgender women: a mixed methods study from the Northern Himalayan region.BMC public health · 2025Article
- Provision of gender-affirming care for trans and gender-diverse adults: a systematic review of health and quality of life outcomes, values and preferences, and costs.EClinicalMedicine · 2025Review
- Systematic review of prospective adult mental health outcomes following affirmative interventions for gender dysphoria.International journal of transgender health · 2025Review
- Gender-Affirming Surgery in Low- and Middle-Income Countries: A Systematic Review.Journal of clinical medicine · 2024Review
- Gender differences in prevalence and clinical correlates of anxiety in first-episode and drug-naïve patients with major depressive disorder comorbid with metabolic syndrome.BMC psychiatry · 2024Article
- Review
- A mini-review of the evidence for cerebrovascular changes following gender-affirming hormone replacement therapy and a call for increased focus on cerebrovascular transgender health.Frontiers in human neuroscience · 2023Review
- Impact of Gender-Affirming Interventions on Mental Health and Body Image Satisfaction of Transgender Individuals: A Systematic Review.Indian journal of endocrinology and metabolismReview
- Gender in Health: Addressing Transgender-Related Stigma and Health Disparities in Southeast Asia.Inquiry : a journal of medical care organization, provision and financingArticle
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Authors and funding
3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
introductionPrevious studies have reported low quality of life scores and a high prevalence of depression among transgender women in Thailand; however, there is still little research on the effects of gender confirmation surgery among this population.
aimThis study aims to prospectively evaluate the overall quality of life, self-esteem, and depression status among male-to-female transgender individuals in Thailand.
methodsThis prospective observational cohort study was conducted between January 2018 and December 2020 and included 41 participants who underwent gender confirmation surgery. All participants underwent a psychiatric evaluation and received 3 sets of questionnaires preoperatively and 6 months postoperatively to evaluate quality of life, self-esteem, and depression: the Thai abbreviated version of the World Health Organization quality of life questionnaire, the Rosenberg Self-Esteem Scale, and the Patient Health Questionnaire-9, respectively. We examined scores from each questionnaire and depression status before and after gender confirmation surgery, with P < .05 considered significant.
main outcome measureThis study's primary outcomes measured quality of life, depression, and self-esteem before and after gender confirmation surgery.
resultsThirty-seven participants completed all sets of questionnaires (response rate 90.2%). The mean age of the participants was 26.2 ± 4.7 years at the time of surgery. Five (13.5%) participants met the criteria for mild depression preoperatively, but none did postoperatively. There were no signs of major depressive disorder, suicidal ideation, or suicidal attempts in any of the participants. There was a significant improvement in quality of life (P < .001) and self-esteem (P < .001), as well as lower depression (P < .001) after gender confirmation surgery. The greatest quality of life improvement was related to participants' sexual relationships.
conclusionMale-to-female gender confirmation surgery significantly contributes to improving quality of life, self-esteem, and depression in Thai transgender women. Persons diagnosed with gender dysphoria who intend to undergo gender confirmation surgery should be supported by healthcare providers in accessing the medical facilities and treatment needed to improve their quality of life. Chaovanalikit T, Wirairat K, Sriswadpong P. Quality of Life, Self-Esteem, and Depression Among Thai Transgender Women Before and After Male-to-Female Gender Confirmation Surgery: A Prospective Cohort Observational Study. Sex Med 2022;10:100533.
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