Evidence map›Paper›PMID 35659655›Full record

Trial reportBMC oral health2022

The influence of two photobiomodulation protocols on orthodontically induced inflammatory root resorption (a randomized controlled clinical trial).

Farah Y Eid, Walid A El-Kenany, Mohamed I Mowafy, Ahmed R El-Kalza

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC oral health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04926389 (The Effect of Two Low-level Laser Irradiation Protocols on the Rate of Canine Retraction), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04926389 naunknown statusnot on this map

The Effect of Two Low-level Laser Irradiation Protocols on the Rate of Canine Retraction (a Randomized Controlled Clinical Trial)

TypeinterventionalSponsorHams Hamed AbdelrahmanRan2020 to 2021Enrolled16ConditionsMalocclusionArmslow-level laser therapy applied on days 0, 3,7,14 & every 2 weeks, low-level laser therapy applied every 3 weeks
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Farah Y EidDepartment of Orthodontics, Faculty of Dentistry, Alexandria University, Champolion Street, Azarita, Alexandria, Egypt. farahyousry66@gmail.com.
Walid A El-KenanyDepartment of Orthodontics, Faculty of Dentistry, Alexandria University, Champolion Street, Azarita, Alexandria, Egypt.
Mohamed I MowafyDepartment of Orthodontics, Faculty of Dentistry, Alexandria University, Champolion Street, Azarita, Alexandria, Egypt.
Ahmed R El-KalzaDepartment of Orthodontics, Faculty of Dentistry, Alexandria University, Champolion Street, Azarita, Alexandria, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundControversial results have been reported regarding the impact of photobiomodulation (PBM) on orthodontically induced inflammatory root resorption (OIIRR). The aim of this study was to evaluate the influence of two PBM protocols, one of them requiring a high application frequency (on days 0, 3, 7, 14, then every 2 weeks), while the second requires less frequent applications (every 3 weeks), on OIIRR accompanying orthodontic treatment.

methodsTwenty female patients were recruited for this randomized controlled trial, requiring the therapeutic extraction of maxillary first premolars, and they were randomly divided into 2 equal groups. In Group A, one side of the maxillary arch randomly received PBM on days 0, 3, 7, 14, and every 2 weeks thereafter, while in Group B, one side was randomly chosen to receive PBM every 3 weeks. The laser applied was a Diode laser with a wavelength of 980 nm, in a continuous mode. Canine retraction in both groups was carried out using closed-coil springs, delivering 150 g of force, and the force level was checked every 3 weeks, over a 12-week study period. Pre-retraction and post-retraction cone-beam computed tomography (CBCT) was done for the evaluation of OIIRR.

resultsNo significant differences in the amount of OIIRR have been reported between the laser and control sides in both groups A and B. Also, no significant differences have been reported between the laser sides in both groups.

conclusionsPhotobiomodulation does not affect OIIRR, whether by increasing or decreasing its occurrence, with both laser application protocols. Therefore, it can be stated that PBM does not result in root resorption less than the commonly observed range elicited with conventional orthodontic treatment, and that it has no effect on OIIRR. Trial registration Two Low-level Laser Irradiation Protocols on the Rate of Canine Retraction (NCT04926389), 15/06/2021-retrospectively registered. https://clinicaltrials.gov/ct2/show/NCT04926389 .

Indexed as

Low-Level Light TherapyRoot ResorptionBicuspidFemaleHumansLasers, SemiconductorTooth Movement TechniquesCone-beam computed tomographyLaserOrthodontically induced inflammatory root resorptionPhotobiomodulation

Identifiers

PMID35659655
PMCPMC9167544

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.