Evidence map›Paper›PMID 35659648›Full record

ArticleBMC public health2022

Excess mortality associated with the COVID-19 pandemic in Latvia: a population-level analysis of all-cause and noncommunicable disease deaths in 2020.

Inese Gobiņa, Andris Avotiņš, Una Kojalo, Ieva Strēle, Santa Pildava, Anita Villeruša, Ģirts Briģis

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.

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  14. The impact of the SARS-CoV-2 pandemic on cause-specific mortality patterns: a systematic literature review.Zeitschrift fur Gesundheitswissenschaften = Journal of public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Inese GobiņaInstitute of Public Health, Riga Stradiņš University, Anninmuizas Boulevard 26a, Riga, LV-1067, Latvia. inese.gobina@rsu.lv.
Andris AvotiņšFaculty of Biology and Faculty of Geography and Earth Sciences, University of Latvia, Jelgavas street 1, Riga, LV-1004, Latvia.
Una KojaloInstitute of Public Health, Riga Stradiņš University, Anninmuizas Boulevard 26a, Riga, LV-1067, Latvia.
Ieva StrēleInstitute of Public Health, Riga Stradiņš University, Anninmuizas Boulevard 26a, Riga, LV-1067, Latvia.
Santa PildavaCentre for Disease Prevention and Control, Duntes 22, k-5, Riga, LV-1005, Latvia.
Anita VillerušaInstitute of Public Health, Riga Stradiņš University, Anninmuizas Boulevard 26a, Riga, LV-1067, Latvia.
Ģirts BriģisDepartment of Public Health and Epidemiology, Riga Stradiņš University, Kronvalda Boulevard 9, Riga, LV-1010, Latvia.
Riga Stradiņš University · LVUniversity of Latvia · LV

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAge-standardised noncommunicable disease (NCD) mortality and the proportion of the elderly population in Latvia are high, while public health and health care systems are underresourced. The emerging COVID-19 pandemic raised concerns about its detrimental impact on all-cause and noncommunicable disease mortality in Latvia. We estimated the timing and number of excess all-cause and cause-specific deaths in 2020 in Latvia due to COVID-19 and selected noncommunicable diseases.

methodsA time series analysis of all-cause and cause-specific weekly mortality from COVID-19, circulatory diseases, malignant neoplasms, diabetes mellitus, and chronic lower respiratory diseases from the National Causes of Death Database from 2015 to 2020 was used by applying generalised additive modelling (GAM) and joinpoint regression analysis.

resultsBetween weeks 14 and 52 (from 1 April to 29 December) of 2020, a total of 3111 excess deaths (95% PI 1339 - 4832) were estimated in Latvia, resulting in 163.77 excess deaths per 100 000. Since September 30, with the outbreak of the second COVID-19 wave, 55% of all excess deaths have occurred. Altogether, COVID-19-related deaths accounted for only 28% of the estimated all-cause excess deaths. A significant increase in excess mortality was estimated for circulatory diseases (68.91 excess deaths per 100 000). Ischemic heart disease and cerebrovascular disease were listed as the underlying cause in almost 60% of COVID-19-contributing deaths.

conclusionsAll-cause mortality and mortality from circulatory diseases significantly increased in Latvia during the first pandemic year. All-cause excess mortality substantially exceeded reported COVID-19-related deaths, implying COVID-19-related mortality during was significantly underestimated. Increasing mortality from circulatory diseases suggests a negative cumulative effect of COVID-19 exposure and reduced access to healthcare services for NCD patients.

Indexed as

Cardiovascular DiseasesCOVID-19Diabetes MellitusNoncommunicable DiseasesAgedCause of DeathHumansLatviaMortalityPandemicsCOVID-19Excess deathsMortalityNoncommunicable diseases

Identifiers

PMID35659648
PMCPMC9163859
OpenAlexW4281759118

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.