ArticleBMC ophthalmology2022
Axial length shortening after orthokeratology and its relationship with myopic control.
Article in BMC ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Efficacy Comparison of Repeated Low-Level Red Light and Low-Dose Atropine for Myopia Control: A Randomized Controlled Trial.Translational vision science & technology · 2022Trial
- Early Axial Length Response Predicts Long-Term Myopia Control in Children Undergoing Orthokeratology.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Real-Life Orthokeratology for Myopia Control in Hungarian Children: A Five-Year Study of Axial Length Changes.Life (Basel, Switzerland) · 2026Article
- Comparative Effectiveness of Myopia-control Spectacle Lenses: Clincial setting Performance from a Retrospective Cohort Study.Ophthalmology science · 2026Article
- Axial length changes and baseline predictors over five years in children treated with orthokeratology lenses: a retrospective cohort study.Frontiers in bioengineering and biotechnology · 2026Article
- Effectiveness of orthokeratology in myopia control during COVID-19 home confinement in Shanghai: a retrospective study.BMC ophthalmology · 2025Article
- Baseline ocular biometrics in children with orthokeratology-induced axial length reduction or elongation.BMC ophthalmology · 2025Article
- Orthokeratology for myopia control: a three-year longitudinal study on axial length modulation influenced by baseline age and spherical equivalent.BMC ophthalmology · 2025Article
- Slowing Myopia Progression in Adolescents Using Orthokeratology: A Retrospective Chart Review.Cureus · 2025Article
- Axial Length Stabilization or Reduction in over 40% of Patients Wearing Extended Depth-of-Focus Contact Lenses.Journal of clinical medicine · 2025Article
- Impact of Orthokeratology on Corneal Morphology, Ocular Health and Myopia Control in Children: A 12-Month Clinical Assessment in Myopic Children Living in Kuala Lumpur, Malaysia.Clinical optometry · 2025Article
- Analysis of axial shortening induced by orthokeratology lenses and its mechanical mechanisms.PloS one · 2025Article
- Effects of orthokeratology lenses on choroidal thickness and choriocapillaris perfusion in myopic children.Frontiers in medicine · 2025Article
- Real-world outcomes of Defocus Incorporated Multiple Segments lenses on retarding axial elongation in myopic children and adolescents.Frontiers in medicine · 2024Article
- Systematic Review of Myopia Progression after Cessation of Optical Interventions for Myopia Control.Journal of clinical medicine · 2023Review
- Repeated Low-Level Red-Light Therapy for Controlling Onset and Progression of Myopia-a Review.International journal of medical sciences · 2023Review
- Axial Length Shortening and Choroid Thickening in Myopic Adults Treated with Repeated Low-Level Red Light.Journal of clinical medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
purposeTo determine the pattern of axial variation in subjects with initial shortened axial length during the entire period of orthokeratology and to discuss the possibility of shortened AL after one month of orthokeratology becoming a predictor of myopia control.
methodThis study retrospectively included 106 children with myopia aged 8 to 14 wearing OK lenses. Fifty-four eyes with shortened axial length (AL) at the first-month visit were enrolled in the axial length shortening (ALS) group, and fifty-two eyes without shortened AL were enrolled in the no axial length shortening (NALS) group. Axial length and refractive error at baseline and within the entire period of orthokeratology (20 months), including fitting, washout period and re-wear, were measured. Eighty-five children who started wearing single vision spectacle were also included as a control group.
resultsIn the ALS group, AL became longer after shortening and slowly exceeded baseline; afterward, AL experienced a rebound during the washout period and shortened again if OK lenses were re-worn. After washout period, significant difference in AL (ALS:0.28 ± 0.19 mm, NALS: 0.52 ± 0.17 mm) and spherical equivalent (ALS:-0.43 ± 0.44D, NALS:-0.91 ± 0.40D) between the two groups were found(P<0.05). The changes in AL and SE were both significantly correlated with the changes in AL at the first-month visit (P<0.05).
conclusionAfter AL is shortened in the initial stage of orthokeratology, it will experience a rapid rebound during the washout period, and the shortening can reappear when re-wearing OK lenses. Hence, the evaluation of orthokeratology will be more objective and accurate after the wash-out period. In addition, the existence and degree of axial shortening can be used as a predictor of long-term myopia development.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.