Evidence map›Paper›PMID 35659318›Full record

ArticleVirology journal2022

Origin and evolution analysis and genetic characteristics of echovirus 9 in China.

Fenfen Si, Tianjiao Ji, Dongyan Wang, Yong Zhang, Shuangli Zhu, Junhan Li, Wenbo Xu, Dongmei Yan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Fenfen SiWHO WPRO Regional Polio Reference Laboratory and NHC Key Laboratory for Biosafety, NHC Key Laboratory for Medical Virology, Chinese Center for Disease Control and Prevention, National Institute for Viral Disease Control and Prevention, Beijing, 102206, People's Republic of China.
Tianjiao JiWHO WPRO Regional Polio Reference Laboratory and NHC Key Laboratory for Biosafety, NHC Key Laboratory for Medical Virology, Chinese Center for Disease Control and Prevention, National Institute for Viral Disease Control and Prevention, Beijing, 102206, People's Republic of China.
Dongyan WangWHO WPRO Regional Polio Reference Laboratory and NHC Key Laboratory for Biosafety, NHC Key Laboratory for Medical Virology, Chinese Center for Disease Control and Prevention, National Institute for Viral Disease Control and Prevention, Beijing, 102206, People's Republic of China.
Yong ZhangWHO WPRO Regional Polio Reference Laboratory and NHC Key Laboratory for Biosafety, NHC Key Laboratory for Medical Virology, Chinese Center for Disease Control and Prevention, National Institute for Viral Disease Control and Prevention, Beijing, 102206, People's Republic of China.
Shuangli ZhuWHO WPRO Regional Polio Reference Laboratory and NHC Key Laboratory for Biosafety, NHC Key Laboratory for Medical Virology, Chinese Center for Disease Control and Prevention, National Institute for Viral Disease Control and Prevention, Beijing, 102206, People's Republic of China.
Junhan LiWHO WPRO Regional Polio Reference Laboratory and NHC Key Laboratory for Biosafety, NHC Key Laboratory for Medical Virology, Chinese Center for Disease Control and Prevention, National Institute for Viral Disease Control and Prevention, Beijing, 102206, People's Republic of China.
Wenbo XuWHO WPRO Regional Polio Reference Laboratory and NHC Key Laboratory for Biosafety, NHC Key Laboratory for Medical Virology, Chinese Center for Disease Control and Prevention, National Institute for Viral Disease Control and Prevention, Beijing, 102206, People's Republic of China.
Dongmei YanWHO WPRO Regional Polio Reference Laboratory and NHC Key Laboratory for Biosafety, NHC Key Laboratory for Medical Virology, Chinese Center for Disease Control and Prevention, National Institute for Viral Disease Control and Prevention, Beijing, 102206, People's Republic of China. dongmeiyan1976@163.com.
National Institute for Viral Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEchovirus 9 (E9) is associated with a wide variety of diseases and medical conditions, and the clinical symptoms of sporadic cases caused by E9 often are severe. With a high global prevalence, E9 has caused multiple outbreaks worldwide. However, little is known about the genetic and geographic population dynamics of E9.

methodA total of 131 VP1 gene sequences, including15 generated in this study and 116 obtained from GenBank, were used to coestimate time-resolved phylogenies to infer viral evolution and transmission in worldwide. Overlapping fragments representing whole genomes were amplified by reverse transcription polymerase chain reaction (RT-PCR) using specific primers. Then, we reported the genetic characteristics of fifteen E9 strains in the Chinese Mainland. Similarity plots and bootscanning analysis were used to determine recombination patterns of E9.

resultsThe estimated mean evolutionary rate of global E9 VP1 gene was 4.278 × 10

conclusionThis study highlights a persistent transmission network of E9 in worldwide, provides valuable information regarding the molecular epidemiology of E9.

Indexed as

Echovirus 9ChinaEnterovirus B, HumanEvolution, MolecularGenome, ViralPhylogenyRecombination, GeneticEchovirus 9Origin and evolution analysisRecombination formsTemperature sensitivity

Identifiers

PMID35659318
PMCPMC9166342
OpenAlexW4281641798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.