Evidence map›Paper›PMID 35659252›Full record

ArticleJournal of neuroengineering and rehabilitation2022

Muscle contributions to pre-swing biomechanical tasks influence swing leg mechanics in individuals post-stroke during walking.

Lydia G Brough, Steven A Kautz, Richard R Neptune

Open access · goldAbstract read
In one paragraph

Article in Journal of neuroengineering and rehabilitation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Deficit in intersegmental torques drives post-stroke stiff-knee gait.medRxiv : the preprint server for health sciences · 2025
    Article
  4. Heteronymous feedback from quadriceps onto soleus in stroke survivors.Journal of neuroengineering and rehabilitation · 2025
    Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Lydia G BroughWalker Department of Mechanical Engineering, The University of Texas at Austin, Austin, TX, USA.
Steven A KautzRalph H Johnson VA Medical Center, Charleston, SC, USA.ORCID 0000-0003-3151-8235
Richard R NeptuneWalker Department of Mechanical Engineering, The University of Texas at Austin, Austin, TX, USA. rneptune@mail.utexas.edu.ORCID 0000-0003-2425-004X
Walker (United States) · USMedical University of South Carolina · US

Funding

Treating Depression and Enhancing Locomotor Recovery Post-strokeP20GM109040 · NIGMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI KAUTZ, STEVEN A. · 2014 to 2024
$23.5M
RR&D Research Career Scientist Award ApplicationIK6RX003075 · VA · RALPH H JOHNSON VA MEDICAL CENTER · PI KAUTZ, STEVEN A. · 2020 to 2025
–
NIGMS NIH HHS P20 GM109040RRD VA I01 RX001935RRD VA IK6 RX003075
6 · The paper itself

Abstract

backgroundSuccessful walking requires the execution of the pre-swing biomechanical tasks of body propulsion and leg swing initiation, which are often impaired post-stroke. While excess rectus femoris activity during swing is often associated with low knee flexion, previous work has suggested that deficits in propulsion and leg swing initiation may also contribute. The purpose of this study was to determine underlying causes of propulsion, leg swing initiation and knee flexion deficits in pre-swing and their link to stiff knee gait in individuals post-stroke.

methodsMusculoskeletal models and forward dynamic simulations were developed for individuals post-stroke (n = 15) and healthy participants (n = 5). Linear regressions were used to evaluate the relationships between peak knee flexion, braking and propulsion symmetry, and individual muscle contributions to braking, propulsion, knee flexion in pre-swing, and leg swing initiation.

resultsFour out of fifteen of individuals post-stroke had higher plantarflexor contributions to propulsion and seven out of fifteen had higher vasti contributions to braking on their paretic leg relative to their nonparetic leg. Higher gastrocnemius contributions to propulsion predicted paretic propulsion symmetry (p = 0.005) while soleus contributions did not. Higher vasti contributions to braking in pre-swing predicted lower knee flexion (p = 0.022). The rectus femoris had minimal contributions to lower knee flexion acceleration in pre-swing compared to contributions from the vasti. However, for some individuals with low knee flexion, during pre-swing the rectus femoris absorbed more power and the iliopsoas contributed less power to the paretic leg. Total musculotendon work done on the paretic leg in pre-swing did not predict knee flexion during swing.

conclusionsThese results emphasize the multiple causes of propulsion asymmetry in individuals post-stroke, including low plantarflexor contributions to propulsion, increased vasti contributions to braking and reliance on compensatory mechanisms. The results also show that the rectus femoris is not a major contributor to knee flexion in pre-swing, but absorbs more power from the paretic leg in pre-swing in some individuals with stiff knee gait. These results highlight the need to identify individual causes of propulsion and knee flexion deficits to design more effective rehabilitation strategies.

Indexed as

LegStrokeBiomechanical PhenomenaGaitHumansKnee JointMuscle, SkeletalWalkingBiomechanicsCompensationGaitModelingStiff knee gait

Identifiers

PMID35659252
PMCPMC9166530
OpenAlexW4281653619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.