Evidence map›Paper›PMID 35659123›Full record

ArticleThe Journal of thoracic and cardiovascular surgery2023

Shooting for the moon: Genome editing for pig heart xenotransplantation.

David K C Cooper, S Sikandar Raza, Ryan Chaban, Richard N Pierson

Open access · bronzeAbstract readEditorial
In one paragraph

Article in The Journal of thoracic and cardiovascular surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Double transgenic neonatal porcine islets as an alternative source for beta cell replacement therapy.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

David K C CooperCenter for Transplantation Sciences, Massachusetts General Hospital and Harvard Medical School, Boston, Mass.
S Sikandar RazaUniversity of Alabama at Birmingham, Birmingham, Ala.
Ryan ChabanCenter for Transplantation Sciences, Massachusetts General Hospital and Harvard Medical School, Boston, Mass; Department of Cardiovascular Surgery, University Hospital of Johannes Gutenberg University, Mainz, Germany. Electronic address: rchaban@mgh.harvard.edu.
Richard N PiersonCenter for Transplantation Sciences, Massachusetts General Hospital and Harvard Medical School, Boston, Mass.
Harvard University · USMassachusetts General Hospital · USUniversity of Alabama at Birmingham · US

Funding

Prolonging life-supported pig kidney and heart graft survival in baboons by suppressing inflammationU19AI090959 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI COOPER, DAVID KC · 2010 to 2024
$26.3M
CRISPR-Modified Cardiac Xenograft TransplantationU01AI153612 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI PIERSON, RICHARD N · 2021 to 2024
$3.2M
CRISPR-Modified Cardiac Xenograft TransplantationR01AI153612 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI PIERSON, RICHARD N · 2020 to 2020
$796k
NIAID NIH HHS R01 AI153612NIAID NIH HHS U01 AI153612NIAID NIH HHS U19 AI090959
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene EditingGraft RejectionAnimalsAnimals, Genetically ModifiedHeartSwineThoraxTransplantation, Heterologousgene editingheartkidneypigxenotransplantation

Identifiers

PMID35659123
PMCPMC10124774
OpenAlexW4229054378

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.