Evidence map›Paper›PMID 35659092›Full record

ReviewClinics in perinatology2022

Lipids and Long Chain Polyunsaturated Fatty Acids in Preterm Infants.

Kristin Santoro, Camilia R Martin

Open access · greenAbstract readReview
In one paragraph

Review in Clinics in perinatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Effect of enteral supplementation of DHA with or without ARA in preterm infants: a meta-analysis.Archives of disease in childhood. Fetal and neonatal edition · 2025
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Postnatal growth restriction impairs rat lung structure and function.Anatomical record (Hoboken, N.J. : 2007) · 2025
    Article
  7. Review
  8. Article
  9. Changes in Gut Microbiota at 1-60 Days in 92 Preterm Infants in a Neonatal Intensive Care Unit Using 16S rRNA Gene Sequencing.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kristin SantoroDivision of Newborn Medicine, Department of Pediatrics, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA; Harvard Medical School, Boston, MA, USA.
Camilia R MartinHarvard Medical School, Boston, MA, USA; Department of Neonatology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Rose3, Boston, MA 02215, USA. Electronic address: cmartin1@bidmc.harvard.edu.
Harvard University · US

Funding

Neonatal Research Training ProgramT32HD098061 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI Stella Kourembanas, Martha C. Sola-Visner · 2019 to 2026
$4.0M
Impact of fatty acid imbalance in intestinal health and disease in prematurityR01DK104346 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI MARTIN, CAMILIA R · 2014 to 2017
$2.8M
NICHD NIH HHS T32 HD098061NIDDK NIH HHS R01 DK104346
6 · The paper itself

Abstract

Fatty acids are critical bioactives for fetal and neonatal development. Premature delivery and current nutritional strategies pose several challenges in restoring fatty acid balance in the preterm infant. The impact on fatty acid balance and outcomes using lipid emulsions, enteral nutrition, and enteral supplements are reviewed, including a summary of the most recent large clinical trials of enteral fatty acid supplementation for the preterm infant. Research gaps remain in successfully implementing nutritional strategies to optimize fatty acid status in preterm infants.

Indexed as

Fatty AcidsInfant, PrematureEnteral NutritionFatty Acids, UnsaturatedHumansInfantInfant, NewbornInfant Nutritional Physiological PhenomenaFatty AcidsFatty Acids, UnsaturatedFatty acidsLipid emulsionsLipidsLipid supplements

Identifiers

PMID35659092
PMCPMC9177057
OpenAlexW4224287753

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.